黄桂颗粒的质量标准研究  

Quality Control of Huanggui Granula

作　　者：牛获山[1] 吴悦涛 韩雪 刘颖 

机构地区：[1]黑龙江中医药大学,150025 [2]黑龙江省呼兰区中医医院,150500 [3]哈药集团世一堂制药厂,150088 [4]北京新创生物工程有限公司,102209

出　　处：《中国中医药现代远程教育》2010年第24期15-16,共2页Chinese Medicine Modern Distance Education of China

摘　　要：目的建立黄桂颗粒的质量标准。方法采用TLC对芍药苷、桂皮醛进行鉴别,采用HPLC测定黄芪甲苷的含量。结果薄层色谱鉴别分离度好,专属性强;黄芪甲苷对照品在125～1000ng呈良好的线性关系,平均加样回收率为98.9%,RSD为1.37%。结论该法简单方便、准确,重现性好,可用于黄桂颗粒的质量控制。Objective To establish a quality standard for Huanggui granula.Methed Adopting TLC method to make a qualitative determination of peony glucoside and cinnamic aldehyde and using HPLC method to determine the content of astragaloside in Radix scutellariae.Result TLC has a high identification and separating degree,strong specificity.The reference substance of astragaloside has a good linear relationship in 125ng ～ 1000ng range.The average recovery is 98.9 %,RSD=1.37 %.Conclusion The method is proved to be simple and specialized with a good reproductivity and can be used to control the quality of Huanggui granula.

关 键 词：质量控制 黄芪甲苷 芍药苷 桂皮醛 高效液相色谱 

分 类 号：R286[医药卫生—中药学]