乳腺良恶性肿瘤患者超声造影定量分析及其意义  

Quantitative analysis of contrast-enhanced ultrasonography in breast tumors

作　　者：黄海燕[1] 徐晓红[1] 

机构地区：[1]广东医学院附属医院超声科,广东湛江524001

出　　处：《广东医学院学报》2011年第1期24-26,共3页Journal of Guangdong Medical College

摘　　要：目的探讨超声造影时间-强度曲线定量参数在乳腺良、恶性肿瘤鉴别诊断意义。方法选取27例乳腺肿瘤患者进行超声造影,应用时间-强度曲线定量技术(伽马系数变值)检测乳腺肿块中心和边缘区域灌注参数(峰值时间、峰值强度、曲线下面积及平均通过时间),比较良、恶性肿瘤不同区域灌注参数的差异。结果 27例经病理检查证实良性13例,恶性14例。恶性肿瘤的灌注参数均高于良性者(P<0.05或0.01)。恶性肿瘤病灶边缘的灌注参数明显高于中心区域(P<0.05或0.01),但良性者差异无统计学意义(P>0.05)。结论时间-强度曲线的定量参数是超声造影中鉴别乳腺良恶性肿瘤的可靠指标。Objective To evaluate the role of time-intensity curve of contrast-enhanced ultrasonography in differential diagnosis between benign and malignant breast tumors.Methods Twenty-seven patients with breast tumors underwent contrast-enhanced ultrasonography.The perfusion indexes including peak time,peak intensity,area under curve and mean transit time were detected in the tumor center and margin using the time-intensity curve（gamma coefficient variable value）,and their differences were compared between benign and malignant neoplasms.Results All cases were diagnosed by pathological examination,with 13 benign and 14 malignant lesions.The perfusion indexes of malignant tumors were superior to those of benign ones（P0.05 or 0.01）.Although the marginal perfusion indexes were higher than those in malignant lesions（P0.05 or 0.01）,there were no statistical differences them in benign lesions（P0.05）.Conclusion The quantitative parameters of time-intensity curve are reliable in the differential diagnosis between benign and malignant breast tumors in contrast-enhanced ultrasonography.

关 键 词：超声造影 乳腺肿瘤 时间-强度曲线 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]