六西格玛管理方法在药师干预临床合理用药中的应用  

Application of 6σ management in pharmacists intervention on clinical rational use of drug

作　　者：岳春雯[1,2] 张鉴[3] 邹文[2] 

机构地区：[1]山东大学药学院,山东济南250012 [2]山东大学第二医院,山东济南250033 [3]山东省立医院,山东济南250021

出　　处：《齐鲁药事》2011年第1期48-50,共3页qilu pharmaceutical affairs

摘　　要：目的了解药师干预前后我院门诊不合理处方用药情况,查找导致不合理用药的主要原因,促进临床合理用药。方法运用六西格玛管理中的DMAIC(定义、测量、分析、改进、控制)五步法,调查处方中存在的不合理用药现状,采用Minitab15统计软件对结果进行分析,查找可能导致药品不合理使用的主要原因并进行干预,对干预前后的数据进行比较,分析六西格玛管理法在药师干预合理用药过程中的作用和效果。结果干预前、后的不合理用药率(缺陷率)分别为8.93%和4.06%(P<0.001),Z值由2.85上升为3.2,差异具有显著性意义。结论应用六西格玛管理法,可使医院管理更加科学化、精细化,从而促进医院药事管理水平的提高,值得推广。OBJECTIVE To analyze the situation of irrational use of drug before and after clinical pharmacists＇ intervention, to find main reasons that lead to irrational use of drug and promote the rational use of drugs in clinical. METHODS The five steps method of DMAIC （ define, measure, analyze,improve, control ）belonging to 6σ management was used to investigate the status of irrational use of drug in prescriptions,analyzed the result using the Minitab 15 to find predominant reasons that might lead to irrational uses of drugs and interfered .with them, and compared the data before the intervention with after, and analyzed the effect of the 6σ management in rational drug use. RESULTS The irrational drug use rates was respectively 8.93% （ before intervention ） and 4.06% （ after intervention） （ P 〈 0. 001 ） , and Z value raised from 2. 85 to 3.2, which showed a statistical significance. CONCLUSION The application of 6σ management could make the hospital administration more scientific and precise, and promote the level of hospital pharmaceutical administration, so it was worthy to expand.

关 键 词：六西格玛管理方法 药师干预 合理用药 

分 类 号：R969.3[医药卫生—药理学]