尿路感染病原菌及其耐药性分析  

Urinary tract infection and drug resistance of pathogens analysis

作　　者：郭晓霞[1] 

机构地区：[1]河南省焦作市人民医院检验科,河南焦作454002

出　　处：《中国医药导报》2011年第9期80-81,共2页China Medical Herald

摘　　要：目的:了解泌尿系统感染病原菌的分布及对常用抗菌药物的耐药情况,为临床合理治疗尿路感染提供依据。方法:对我院2008年1月～2010年9月尿液培养阳性的632株病原菌的鉴定及药敏结果进行分析。结果:632株病原菌中,革兰阴性杆菌394株(62.3%)。革兰阳性球菌158株(25.0%),真菌80株(12.7%),超广谱β-内酰胺酶(ESBLS)大肠埃希菌和肺炎克雷伯菌分别达50.1%和49.6%;屎、粪肠球菌对高浓度庆大霉素耐药率分别达78.7%和53.8%;耐甲氧西林凝固酶阴性葡萄球菌(MRSCN)达76.1%,呈现对抗菌药物的多重耐药。结论:尿路感染病原菌以革兰阴性杆菌居多,细菌耐药率较高,临床医生应根据培养和药敏结果合理使用抗菌药物。Objective： To investigate the pathogen distribution of the urinary tract infections and drug resistance of the commonly used antimicrobial drugs,provides evidence for clinical rational treatment with urinary infection.Methods： Ana-lyzed the pathogen identified and the antimicrobial susceptibility test results of 632 strains of urine culture positive from January 2008 to September 2010.Results： Of the 632 strains of pathogenic,Gram-Negative bacillus was 394 strains（62.3%）.Gram positive coccus was 158 strains（25.0%）,fungi was 80 strains（12.7%）,super broad-spectrum beta-lactamase（ESBLS） escherichia coli and pneumonia crayresearch bacterium was 50.1% and 49.6% respectively;Excrement,dung en-terococcus resistant to high concentration gentamycin respectively was 78.7% and 53.8%;Resistance to armor oxygen furbenicillin coagulase-negative staphylococcus aureus（MRSCN） reach 76.1%,present to the multiple antimicrobial drug resistance.Conclusion： Urinary infection with gram-negative bacilli pathogenic bacteria resistant majority,higher,clinical doctors should according to cultivate and antimicrobial susceptibility test results rational use of antimicrobial agents.

关 键 词：尿路感染 病原菌 耐药性 

分 类 号：R446.12[医药卫生—诊断学]