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机构地区:[1]西南民族大学生命科学与技术学院,四川成都610041 [2]西南民族大学校医院,四川成都610041
出 处:《安徽农业科学》2011年第6期3630-3632,共3页Journal of Anhui Agricultural Sciences
摘 要:[目的]从传统中草药及其复方中开发高效、长效、广谱、低毒、价廉的抗病毒新药。[方法]以祛邪药白花蛇舌草、金银花和扶正药黄芪、甘草等组成抗病毒复方制剂,用于鸡新城疫(ND)、鸡传染性法氏囊病(IBD)、鸭病毒性肝炎(DVH)、H9亚型禽流感(AI)和禽肿头综合征等疾病自然发病家禽的治疗。同时,以单体黄芪多糖饲喂家禽作为对照。[结果]中药复方制剂对ND、IBD、DVH、AI和禽肿头综合征治疗的有效率分别为87%、87%、69%、100%、100%,均高于黄芪多糖;其痊愈率分别为33%、37%、13%、69%、75%,均显著高于黄芪多糖(P<0.01);其治疗效果较差的病例百分比分别为15%、21%、24%、6%、7%,均显著低于黄芪多糖(P<0.01)。[结论]中药复方对某些家禽病毒性疾病的治疗效果较好,在降低死亡率和促进生产性能方面优于单体黄芪多糖。[Objective] To develop a new antiviral agent with high and long efficacy,wide spectrum,low toxicity and low cost from traditional Chinese herbal medicine and their compound.[Method] The "Quxie"(i.e.,eliminating pathogenic factors) drugs including Hedyotis diffusa and Lonicera japonica and "Fuzheng"(i.e.,strengthening body resistance) drugs including Radix astragali and Glycyrrhiza uralensis were taken to form an antiviral herbal compound preparation.Taking the astragalus polysaccharide monomer as control,the experiment was constructed by usingthe agent to treat some naturally occurring viral diseases,including Newcastle disease(ND),infectious bursal disease(IBD),duck viral hepatitis(DVH),avian influenza(AI) H9 subtype and avian swollen head syndrome.[Result] The effective rates of the agent for treatment of the above-mentioned diseases were 87%,87%,69%,100% and 100%,respectively,which were higher than that of astragalus polysaccharide monomer.The cure rates for these diseases were 33%,37%,13%,69% and 75%,respectively,which were significantly higher than that of astragalus polysaccharide monomer(P0.01).The rates of poor therapeutic efficacy were 15%,21%,24%,6% and 7%,respectively,which were significantly lower than that of astragalus polysaccharide monomer(P0.01).[Conclusion] The Chinese herbal compound preparation shows good therapeutic effects on some avian viral diseases,which can decrease mortality rate and improve production performance of poultry more greatly than astragalus polysaccharide monomer.
分 类 号:S858.21[农业科学—临床兽医学]
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