夜宁胶囊的成型工艺研究  

Study on Molding Process of Night-ning Capsule

作　　者：魏增余[1] 徐连明[2] 丁青龙[3] 李莹[3] 

机构地区：[1]连云港中医药高等职业技术学校,江苏连云港222006 [2]江苏康缘药业股份有限公司,江苏连云港222001 [3]中国人民解放军第102医院,江苏常州223003

出　　处：《现代中药研究与实践》2011年第2期52-54,共3页Research and Practice on Chinese Medicines

摘　　要：目的研究夜宁胶囊的成型工艺。方法分别考察干粉的粉体及颗粒的物理特性(吸湿率、休止角及堆密度等)。结果干粉的吸湿性较大、休止角较小;颗粒的流动性较差;通过制粒可以改善粉体的引湿性及休止角,更有利于装胶囊。结论夜宁胶囊提取物宜制成颗粒,改善粉体物理特性后进行灌装胶囊,提高成品率。Objective To study the molding process of night-ning capsule.Methods Survey physical characteristics of the dry powder and the particle including hygroscopicity,angle of repose and bulk density,respectively.Results The dry powder has major hygroscopicity and minor angle of repose,and particle has minor fluidity.The hydroscopicity and angle of repose can be improved by granulation which can make the capsule loading easier.Conclusion The extracts of night-ning capsule is suitable to make the particle,and the yield of capsule is increased after improving the particle physical characteristics.

关 键 词：夜宁胶囊 粉体 休止角 吸湿性 物理特性 

分 类 号：R944.5[医药卫生—药剂学]