济南市城市居民慢性阻塞性肺病现状调查及相关危险因素分析  

Epidemiological status and related risk factors of COPD in urban residents in Jinan

作　　者：王川[1] 马德东[1] 肖伟[1] 张玉可[1] 姜园园[1] 何宝龙[1] 张一[1] 王洪超[1] 许霞[1] 季秀丽[1] 王琴[1] 王得翔[1] 孙丛丛[1] 陈宏礼[1] 吴瑕[1] 

机构地区：[1]山东大学齐鲁医院呼吸内科,济南250012

出　　处：《山东大学学报（医学版）》2011年第2期128-132,共5页Journal of Shandong University:Health Sciences

摘　　要：目的获得济南城市居民慢性阻塞性肺疾病(COPD)患病率,了解COPD的诊治现状,分析COPD相关危险因素。方法采用横断面多级抽样的方法,对济南市城区内年龄≥40岁的人群进行调查。被调查者填写调查问卷(参考GOLD委员会COPD负担研究专题的流行病学调查问卷,结合我国国情制定统一问卷),应用CHEST-HI801便携式肺功能仪对被调查者进行肺通气功能测定,参照中华医学会呼吸病学分会制定的COPD诊治指南(2007年修订版),确定诊断。结果按规则抽样应该调查的人数为2 467人,实际完成调查问卷和肺通气功能检查者为2 055人;符合COPD诊断者为156例,总体患病率为7.6%,男性患病率为12.2%(111/156),女性患病率为3.9%(45/156);156例COPD患者中既往已被确诊有84例(53.8%),其中无正规治疗者37例(44.0%),之前从未诊断者72例(46.1%),无临床症状者48例(30.8%);应用多因素Logistic回归分析,影响COPD患病的主要因素有:吸烟,男性,高龄,低收入及呼吸病家族史。结论济南市40岁以上城市居民COPD的总体患病率为7.6%,其诊断和治疗现状远不能令人满意,COPD的相关危险因素涉及个体、家庭和社会多个方面。Objective：To obtain the prevalence of chronic obstructive pulmonary disease（COPD） in urban residents in Jinan,to learn the status of diagnosis and treatment and to explore the possible related risk factors.Methods：A cross-sectional study with a multi-stage stratified random sampling method was performed to select subjects aged ≥ 40 years.A questionnaire,designed with reference to the epidemiological questionnaire made by the program of COPD burden of GOLD committee and the practical situation of China,was used in interviews of the subjects.Then the CHEST HI-801 spirometer was used to test lung function in those who finished the questionnaire.The diagnosis of COPD was based on the standard made by the COPD group of Chinese Medical Association（2007 version）.Results：According to the sampling rule,2467 subjects should be included,among whom 2055 subjects finished the questionnaire and spirometry.The overall prevalence of COPD in urban residents in Jinan was 7.6%（156/2055）,12.2%（111/156） in males and 3.9%（45/156） in females.84cases had been confirmed,in which only37（44.0%） cases accepted regular treatment,and48（30.8%） cases were asymptomatic.Multivariate logistic regression analysis found that the main factors affecting the state of COPD were smoking,males,senility,low income and a family history of respiratory diseases.Conclusion The overall prevalence of COPD in urban residents aged≥ 40years in Jinan was7.6%.The actual state of diagnosis and treatment is far from satisfactory.Risk factors of COPD are related to individuals,family,and society.

关 键 词：肺疾病 慢性阻塞性 危险因素 流行病学 

分 类 号：R563[医药卫生—呼吸系统]