静脉吸毒人群HIV、HCV、HBV和梅毒螺旋体感染的血清学检测结果分析  

The Infections of HIV,HCV,HBV and Treponema Pallidum among Drug-injecting Users

作　　者：张宗辉[1] 何永[1] 赵明才[2] 王强[2] 张国元[2] 

机构地区：[1]南充市疾病预防控制中心 [2]川北医学院附属医院,四川南充637000

出　　处：《川北医学院学报》2011年第1期62-64,共3页Journal of North Sichuan Medical College

摘　　要：目的:了解静脉吸毒人群HIV、HCV、HBV及梅毒螺旋体的感染现状。方法:收集362名静脉吸毒人员血液标本,采用酶联免疫吸附试验(ELISA)检测血清抗HIV抗体、抗HCV抗体、HBsAg;采用TRUST试验检测梅毒螺旋体非特异性抗体。结果:362名静脉吸毒人群HIV感染率为4.14%,抗HCV抗体检出率为80.39%,HBsAg检出率为14.92%,梅毒螺旋体非特异性抗体检出率为9.94%,男、女静脉吸毒者感染梅毒螺旋体经统计学分析有显著性差异(p<0.05),静脉吸毒者丙肝病毒感染与年龄显著相关(p<0.05)。结论:静脉吸毒者是感染HIV、HCV、HBV及梅毒螺旋体的高危人群,开展高危人群血清抗HIV抗体、抗HCV抗体、HBsAg及梅毒血清学试验有利于及时发现感染者和控制传染源,降低艾滋病、丙肝、乙肝和梅毒等疾病的传播流行。Objective：To investigate the infections of HIV,HCV,HBV and Treponema pallidum among drug-injecting users.Methods： A total of 362 drug-injecting users were enrolled in this investigation.The quantitation of HIV antibody,HCV antibody and HBsAg were detected by enzyme-linked immunosorbent assay（ELISA）.The titer of non-specific antibody to Treponema pallidum was tested by Syphilis Toluidine Red Untreated Serum Test（TRUST）.Results： Among 362 cases,the rate of HIV infection was 3.59%,the detectable rate of HCV,HBsAg and Syphilis was 80.39%,14.92% and 9.94% respectively.There were highly significant differences by statistic treatment among the cases between male and female who infected Syphilis.Conclusion： Drug-injecting users are risk for HIV、HCV、HBV and Treponema pallidum.Surveillance of drug-injecting users should be strengthened and measures should be taken to control these diseases effectively.Our findings may be used to guide prevention strategies.

关 键 词：艾滋病病毒 丙型肝炎病毒 乙型肝炎病毒 梅毒螺旋体 静脉吸毒 血清学 

分 类 号：R115[医药卫生—公共卫生与预防医学]