微生态制剂局部给药加速残余创面愈合临床研究  

Micro-ecological pharmaceutics administration for accelerating residual wound healing

作　　者：毕波[1] 周慧敏[2] 杨平[3] 朱志军 刘天一[3] 

机构地区：[1]复旦大学附属华东医院,上海市200041 [2]复旦大学附属华东医院检验科,上海市200041 [3]复旦大学附属华东医院整形外科,上海市200041 [4]青岛市立医院烧伤整形外科,山东省266011

出　　处：《中华实用诊断与治疗杂志》2011年第3期232-234,共3页Journal of Chinese Practical Diagnosis and Therapy

基　　金：国家自然科学基金(30973130)

摘　　要：目的:探讨采用乳酸杆菌活菌局部定植治疗残余创面的临床效果。方法:观察组30例残余创面清洁后乳酸杆菌活菌撒布创面,对照组35例常规聚维酮碘消毒换药。观察2组创面愈合情况、愈合时间及乳酸杆菌定植率。结果:观察组乳酸杆菌定植显效率为93%,创面愈合时间明显短于对照组。结论:乳酸杆菌活菌定植法可抑制残余创面高致病性耐药细菌生长和定植,加速创面愈合,是一个安全,有效地治疗方法。Objective To investigate clinical healing effect of Lactobacillus on residual wound.Methods The observation group（n=30） was treated with Lactobacillus perfusing on the wounds.Control group（n=35） was treated with traditional povidone iodine washing and bandaging.The wound healing status,healing time and Lactobacillus colonization rate were observed.Results The effective rate of Lactobacillus colonization in observation group was 93%.The healing time of observation group was shorter than that of control group.Conclusion Lactobacillus administration can inhibit the homo-pathogenicity drug-resistant bacteria colonization and growth on the residual wounds,and accelerate the recovery of residual wounds.It is a safe and effective method.

关 键 词：残余创面 乳酸杆菌 微生态 

分 类 号：R644[医药卫生—外科学]