26例IgM型丙型肝炎抗体阳性患者回顾性分析  

Retrospective analysis of 26 patients with positive IgM antibody to HCV

作　　者：马玲娟[1] 夏季[2] 夏宇[3] 严俊[4] 蔡晋[1] 府伟灵[1] 

机构地区：[1]第三军医大学西南医院检验科,重庆400038 [2]第三军医大学大坪医院野战外科研究所检验科,重庆400042 [3]中国人民解放军第四○一医院检验科,山东青岛266100 [4]第三军医大学新桥医院内分泌科,重庆400037

出　　处：《国际检验医学杂志》2011年第3期333-334,共2页International Journal of Laboratory Medicine

摘　　要：目的分析IgM型丙型肝炎抗体（HCV IgM）阳性患者血清丙氨酸氨基转移酶（ALT）、天门冬氨酸氨基转移酶（AST）、胆红素水平以及乙型肝炎表面抗原（HBsAg）检测结果,为临床诊治提供参考。方法收集2010年1~6月该院26例HCV IgM阳性患者的临床资料进行回顾分析。结果该院就诊人群HCV IgM阳性率为5.0%。在26例HCV IgM阳性患者中,血清ALT水平升高者占34.6%,AST水平升高者占30.8%,胆红素水平升高者占15.4%,合并HBsAg阳性者占7.7%。结论 HCV IgM检测可用于丙型肝炎早期感染的初步筛查,与血清ALT、AST以及胆红素水平具有一定的相关性。丙型肝炎与乙型肝炎双重感染情况日趋多见,应重视对此类患者的早期诊治,以有效控制病情。Objective To investigate serum alanine aminotransferase （ ALT）, aspartate aminotransferase （ AST）, biliruhin and hepatitis B surface antigen（ HBsAg）of 26 patients with positive IgM antibody to HCV（ HCV IgM）, and provide evidence for clinical diagnosis and therapy. Methods A retrospective survey was done with 26 cases of positive HCV IgM in our hospital from January to June in 2010. Results The positive rate of serum HCV IgM of patients in our hospital was 5.0%. Among the 26 cases of posl rive HCV IgM,34.6% ,30.8% and 15.4% of them appeared with abnormally increased level of ALT,AST and bilirubin respective ly. Besides, 7.7 % of them were combined with positive HBsAg. Conclusion The detection of HCV IgM can be applied to preliminary screening for early stage of HCV infection,which has some relation with ALT,AST and bilirubin. Dual infection of HBV and HCV appears more frequently,so we should pay more attention to early diagnosis and therapy.

关 键 词：肝炎病毒属 免疫球蛋白M 丙氨酸转氨酶 肝炎病毒 乙型 

分 类 号：R512.63[医药卫生—内科学]