Entropy Production Rate Changes in Lysogeny/Lysis Switch Regulation of Bacteriophage Lambda  

作　　者：丁辉 罗辽复 林吴 

机构地区：[1]Key Laboratory for Neuroinformation of Ministry of Education, Center of Bioinformatics, School of Life Science and Technology, University of Electronic Science and Technology of China [2]Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University

出　　处：《Communications in Theoretical Physics》2011年第2期371-375,共5页理论物理通讯（英文版）

基　　金：Supported by the National Natural Science Foundation of China under Grant Nos.11047180,90403010,and 200408020102;Scientific Research Startup Foundation of University of Electronic Science and Technology of China

摘　　要：According to the chemical kinetic model of lysogeny/lysis switch in Escherichia coli （E. coil） infected by bacteriophage A, the entropy production rates of steady states are calculated. The resuits show that the lysogenic state has lower entropy production rate than lyric state, which provides an explanation on why the lysogenic state of A phage is so stable. We a/so notice that the entropy production rates of both lysogenic state and lyric state are lower than that of saddle-point and bifurcation state, which is consistent with the principle of minimum entropy production for living organism in nonequilibrium stationary state. Subsequently, the relations between CI and Cro degradation rates at two bifurcations and the changes of entropy production rate with CI and Cro degradation are deduced. The theory and method can be used to calculate entropy change in other molecular network.

关 键 词：lysogeny/lysis switch entropy production rate stationary state BIFURCATION 

分 类 号：O414.11[理学—理论物理]