可降解医用镁基生物材料的研究进展  

Research Progress of Mg-Based Alloys as Degradable Biomedical Materials

作　　者：袁广银[1] 张佳[1] 丁文江[1] 

机构地区：[1]上海交通大学轻合金精密成型国家工程研究中心,上海200240

出　　处：《中国材料进展》2011年第2期44-50,共7页Materials China

基　　金：上海市基础研究重点项目(08JC141412200)

摘　　要：生物体内可降解吸收材料是生物材料发展的重要方向,由于金属材料具有较好的强度和塑韧性,因此金属基可降解吸收材料具有重要的临床应用价值。镁是所有金属材料中生物力学性能与人体骨最接近的金属材料,具有理想的生物力学相容性,因此,镁合金作为可降解生物材料具有巨大的应用潜力。首先介绍了镁基材料作为生物体内可降解植入材料的优点,然后简要回顾了镁基可降解生物材料的早期研究情况,同时系统地介绍和总结了目前的研究进展和遇到的挑战,最后展望了镁合金医用材料的应用前景和发展方向。Biodegradable absorbent material in vivo is an important direction for the development of biological materials;and metal-based biodegradable absorbent materials are of vital clinical value since metal material has preferable strength and plastic toughness.As metal material with closest biomechanical properties to those of human bone,magnesium has ideal biomechanical compatibility and its alloys have great application potential as biodegradable materials therefore.The advantages of magnesium-based alloys as biodegradable implants are presented first.Then the early research history about biomagnesium is briefly reviewed;and current research progress and facing challenges of biomagnesium are introduced and summarized meanwhile.Finally,the future directions and research priorities of medical degradable magnesium-based biomaterials are discussed.

关 键 词：镁合金 生物可降解材料 骨科内植物 血管支架材料 

分 类 号：R318.08[医药卫生—生物医学工程]