血液透析联合血液灌流治疗尿毒症继发性甲状旁腺功能亢进症的疗效观察  

The effect of hemodialysis combination with hemoperfusion on chronic renal failure patients with secondary hyperparathyroidism

作　　者：聂小兰[1] 李婧[1] 邓彦彦[1] 韩鹏勋[1] 

机构地区：[1]深圳市中医院血液净化科,518033

出　　处：《国际护理学杂志》2011年第1期40-42,共3页international journal of nursing

摘　　要：目的 观察血液透析联合血液灌流对慢性肾衰竭（CRF）维持血液透析患者甲状旁腺功能亢进症的疗效.方法 选取2006年1月至2009年1月深圳市中医院血液透析患者50例,并随机分为两组：常规血液透析组（HD组）、血液透析联合血液灌流组（HD＋HP组）.HD组行常规血液透析治疗,每周2～3次,HD＋HP组在血液透析的基础上联合血液灌流治疗,每周2～3次血液透析,联合血液灌流1次,比较两组患者治疗前及治疗12周后血清钙（Ca）、磷（P）和血清全段反应性甲状旁腺激素（iPTH）的浓度.结果 HD＋HP组患者血清P3＋和iPTH下降明显,血清Ca2＋增高.结论 血液透析联合血液灌流可以明显改善CRF维持血液透析患者的继发甲状旁腺功能亢进,并改善其临床症状.Objective To observe the effeet of hemodialysis （HD） combination with hemoperfusion （HP） on chronic renal failure patients with secondary hyperparathyroidism. Methods A total of 50 cases of hemodialysis patients from January 2006 to January 2009 were divided into HD group and HD ＋ HP group. HD group was treated with single HD two or three times per week. HD ＋ HP group was treated with HD two or three times per week in connection with HP one time per week. The serum calcium （Ca）, phosphorus （P） and intact parathyroid hormone （iPTH） concentrations were compared at 0 w and 12 w between two groups. Results The levels of serum P and iPTH were significantly decreased while serum Ca was increased in HD ＋ HP group. Conclusions HD combination with HP could significantly increase the blood calcium level in the CRF patients with secondary hyperparathyroidism and improve their clinical symptoms.

关 键 词：血液透析 血液灌流 甲状旁腺功能亢进 

分 类 号：R692.5[医药卫生—泌尿科学]