空降兵跳伞后血浆的生化变化:初步调查与分析(英文)  

Biochemical Changes of Plasma in Paratroops after Parachuting:A Preliminary Investigation *

作　　者：邬堂春[1] 熊一力[1] 陈胜[1] 冷顺堂[1] 海涛[1] 

机构地区：[1]同济医科大学职业医学研究所

出　　处：《航天医学与医学工程》1999年第4期235-239,共5页Space Medicine & Medical Engineering

摘　　要：目的探讨跳伞期间空降兵经历的生理和心理应激是否会改变空降兵血浆的生化指标。方法调查了对照组（未跳伞组）和跳伞组空降兵血浆和血清中激素水平（皮质醇、生长激素、胰岛素、胰高血糖素、类皮素、血管紧张素Ｉ和ＩＩ、醛固酮）、酶活性（超氧化物岐化酶、谷胱甘肽过氧化氢酶和谷胱甘肽硫转移酶）、自由基损伤指标水平（丙二醛，）、肿瘤坏死因子α（ＴＮＦα）和主要热应激蛋白（ＨＳＰ７０）的差异性。结果跳伞组血清中生长激素、胰岛素、血管紧张素Ｉ、肾素活性和血浆中丙二醛、ＴＮＦα、ＨＳＰ７０等的水平比对照值显著高。结论这些变化有可能作为评估空降兵是否经历异常应激、评价他们的健康状况和选择空降兵的有用生物标志物，但需进一步研究。Objective To study whether physiological and psychological stresses during parachuting jumps may result in biochemical changes of plasma in parachutists. Method Differences in the levels of hormones (cortisol, growth hormone, insulin, pancreatic glucagon, endothelin, angiotonin I and II, aldosterone), activities of enzymes (superoxide dismutase, glutathione peroxidase, glutathione S transferase), levels of the free radical damage indicator malondialdehyde (MDA), tumor necrosis factor alpha (TNF α), and the main heat stress protein, HSP70,in the plasma and serum were investigated in control (non parachuting) and parachuting paratroops. Result Significantly higher levels of serum hormones such as growth hormone, insulin, angiotonin I, renin activities, as well as MDA and plasma TNF α and HSP70 were observed in the parachuting group. Conclusion Whether these changes can potentially serve as useful biomarkers to assess possible abnormal stress in parachutists and to evaluate the health condition and to select parachutists remains to be further studied.

关 键 词：空降兵 跳伞 激素 热应激蛋白 血浆 生化指标 

分 类 号：R852[医药卫生—航空、航天与航海医学]