动脉栓塞术治疗移植肾晚期功能衰竭合并移植物不耐受综合征的安全性和疗效  

Safety and Effectiveness of Percutaneous Embolization for Late Failed Renal Allograft in Patients with Graft Intolerance Syndrome

作　　者：薛翀[1,2] 李汉忠[1] 纪志刚[1] 谢燚[1] 韩精超[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院泌尿外科,北京100730 [2]浙江大学医学院附属第二医院泌尿外科,杭州310009

出　　处：《中国医学科学院学报》2011年第1期76-79,共4页Acta Academiae Medicinae Sinicae

摘　　要：目的探讨动脉栓塞术治疗晚期移植肾功能衰竭合并移植物不耐受综合征的安全性和疗效。方法对18例移植肾晚期功能衰竭合并移植物不耐受综合征患者,选择行移植肾动脉栓塞术,评估栓塞术并发症、术后症状缓解率及预后。结果 15例（83.3%）患者移植物不耐受症状缓解,其中6例（33.3%）患者术后出现发热和移植肾区疼痛加重,平均持续3.5 d（2~5d）后缓解。3例（16.7%）患者症状持续2周以上,最后行手术切除。无严重栓塞并发症发生。结论移植肾动脉栓塞术可以避免移植肾晚期功能衰竭外科手术切除,可作为一种治疗移植肾晚期功能衰竭后合并移植物不耐受综合征的安全有效的方法。Objective To investigate the clinical safety and effectiveness of percutaneous embolization in treating the late failed renal allograft in patients with graft intolerance syndrome（GIS）.Methods Transcatheter embolization of renal graft artery was performed in 18 patients with late graft dysfunction and GIS.The subsequent complications,postoperative symptom remission rate,and prognosis were assessed.Results GIS was relieved in 15 patients（83.3%）,of which 6 patients（33.3%） had severer fever and pain in the area of renal graft after embolization,which lasted for a mean of 3.5 days（range： 2-5 days）.GIS persisted for more than 2 weeks in 3 patients（16.7%）,who ultimately underwent surgical removal of grafts.No severe embolism-associated complications were noted.Conclusion Percutaneous embolization can effectively avoid surgical graft removal in patients with late renal allograft failure,and therefore can be used as a safe and effective treatment for the late failed renal allograft combined with GIS.

关 键 词：肾切除术 动脉栓塞 移植肾功能衰竭 移植物不耐受综合征 

分 类 号：R692.9[医药卫生—泌尿科学]