心尖肥厚型心肌病患者188例临床特点及预后  

Cfinical features and prognosis of 188 Chinese patients with apical hypertrophic cardiomyopathy

作　　者：陶永康[5] 闫丽荣[1,2,3,4] 李一石[1,2,3,4] 顼志敏[1,2,3,4] 张国强[6] 祖丽梅[7] 杜海燕[7] 樊朝美[1,2,3,4] 

机构地区：[1]中国医学科学院,100037 [2]北京协和医学院 [3]阜外心血管病医院临床药理中心 [4]卫生部心血管药物临床研究重点实验室 [5]卫生部中日友好医院急诊科 [6]中日友好医院急诊科 [7]内蒙古医学院附属医院内科

出　　处：《中华心血管病杂志》2011年第2期106-109,共4页Chinese Journal of Cardiology

摘　　要：目的 研究中国人心尖肥厚型心肌病（AHCM）的临床特点及预后。方法 对188例AHCM患者进行回顾性分析及随访，并对其临床表现、心血管原性病死率及心血管事件发生率进行分析。结果 188例AHCM患者中男性139例（73．9％），女性49例（26．1％），占同期肥厚型心肌病患者的16．0％，平均年龄（51．9±12．6）岁。其中，单纯型AHCM患者120例（63．8％），混合型AHCM患者68例（36．2％）。171例（91．0％）患者平均随访时间（5．0±3．0）年，2例发生心血管原性死亡，心血管原性总病死率为1．2％，随访期间共28例（16．4％）患者发生心血管事件。结论 中国人AHCM患病率较高，单纯型AHCM多见，预后较好。Objective To analyze the clinical characteristics and prognosis of Chinese patients with apical hypertrophic cardiomyopathy （AHCM）. Methods A total of 188 patients with AI-ICM diagnosed at Fuwai Hospital were included in this retrospective study. Clinical characteristics, mortality and cardiovascular morbidity were analyzed. A multiple logistic regression was performed to adjust for potential confounding factors. Results Males predominated with a number of 139 （73.9%） in this cohort. Patient＇s age ranged from 15 to 81 （51.9±12. 6） years. There were 120 patients （63. 8% ） with ＂pure＂ type and 68 patients （36.2%） with ＂ mixed＂ type of AHCM, 171 patients were followed up for （5.0±3.0）years, cardiovascular mortality was 1.2%, 28 patients （16.4%） experienced one or more cardiovascular events. Conclusion The prevalence of AHCM is high in Chinese HCM patients, pure type AHCM is more common, and AHCM patients have a benign clinical course.

关 键 词：心肌病 肥厚性 预后 

分 类 号：R542.2[医药卫生—心血管疾病]