左卡尼汀对治疗老年维持性血液透析患者低血压和肌肉痉挛的疗效观察  

The therapeutic effects of L-carnitine in treating hypotension and muscle spasm in elderly patients with maintenance hemodialysis

作　　者：沈文清[1] 梁波[1] 钱捷[1] 梁敏灵[1] 黄丽[1] 

机构地区：[1]广州医学院第三附属医院肾内科,广州510150

出　　处：《临床医学》2011年第3期27-29,共3页Clinical Medicine

摘　　要：目的观察静脉补充左卡尼汀对老年血液透析患者透析中低血压、肌肉痉挛的影响。方法 31例维持性血液透析患者每次透析结束后应用左卡尼汀1.0 g静脉注射,12周后观察比较患者治疗前后低血压、肌肉痉挛的发生情况。结果注射左卡尼汀可以明显降低患者透析中低血压和肌肉痉挛的发生率。结论左卡尼汀可安全有效地改善患者低血压和肌肉痉挛症状。Objective To investigate the effects of intravenous usage of L-carnitine on treating hypotension,muscle spasm and its mechanism in elderly patients with hemodialysis.Methods L-carnitine（1 g） was infused to thirty-one patients accepting maintenance hemodialysis at the end of each dialysis treatment for 12 weeks.The incidence of hypotension,muscle spasm were observed and compared.Results Intravenous L-carnitine could significantly decrease the incidences of hypotension and muscle spasm（P0.01）.Conclusion Treatment of L-carnitine decreases the incidences of hypotension and muscle spasm in elderly patients with maintenance hemodialysis safely and effectively.

关 键 词：左卡尼汀 维持性血液透析 低血压 肌肉痉挛 

分 类 号：R459.5[医药卫生—治疗学]