鸡贫血因子病全身免疫功能变化的研究  

Study on Changes of Systemic Immune Function of Chicken Infected with Chicken Anemia Virus

作　　者：刘忠贵[1] 杨丽萍[1] 周志勇[1] 李广兴[1] 阿合买提.买买提 

机构地区：[1]东北农业大学动物医学院

出　　处：《黑龙江畜牧兽医》1999年第8期1-3,共3页Heilongjiang Animal Science And veterinary Medicine

基　　金：黑龙江省自然科学基金

摘　　要：用鸡贫血病毒（ＣＡＶ）感染１日龄ＡＡ雏鸡，以未感染同龄ＡＡ雏鸡为对照，感染后不同时间检测其外周血液Ｔ、Ｂ细胞数量和ＩｇＧ、ＩｇＭ、ＩｇＡ含量；胸腺、法氏囊、脾脏ＩｇＧ＋、ＩｇＭ＋、ＩｇＡ＋抗体生成细胞和Ｔ细胞数量以及Ｔ、Ｂ细胞增殖功能；胸腺和脾脏白细胞介素２（ＩＬ－２）和干扰素（ＩＦＮ）诱生活性等的动态变化。The one-day-old chicken were infected with chicken anemia.At different period after infection the experimental chickens were undertaken to study number of T cells and B cells as well as the content of IgG,IgM,IgA in the serum,the number of IgG +,IgM +,IgA + antibody producing cells and T cells along with the T and B cells proliferative response in thymus,Bursa Fabricius and spleen,and the inductive activity of interlukine-2(IL-2) and interferon(IFN) in thymus and spleen.The results incdicated that the systemic cellular and humoral immunity and immunoreguration decreased markedly in comparison with the control chickens.

关 键 词：鸡贫血因子病 AA雏鸡 抗体生成细胞 免疫球蛋白 

分 类 号：S858.312.4[农业科学—临床兽医学]