人工神经网络应用于光谱分析同时测定增效联磺片三组分含量  

Simultaneous Determination of Multi\|Component of Zengxiao Lianhuang Tablet by Using Artificial Nerual Network\|Spectrophotometry

作　　者：严拯宇[1] 王朝晖[2] 姜新民[1] 张圣华 

机构地区：[1]中国药科大学分析化学教研室,南京210009 [2]华中师范大学,武汉430072

出　　处：《分析科学学报》1999年第4期297-301,共5页Journal of Analytical Science

摘　　要：应用人工神经网络原理，采用误差反向传播方法，对紫外吸收光谱重叠的增效联磺片中的三个组分含量不经分离可同时进行测定 。磺胺嘧啶（ＳＤ）、磺胺甲口恶口坐（ＳＭＰ）、甲氧苄胺嘧啶（ＴＭＰ）的平均回收率分别为１０３．１％ 、９８．２１％ 、９８．７６％ 。探讨了人工神经网络中网络参数对分析结果的影响。实验证明，人工神经网络方法应用在光谱分析中对复方药物含量进行测定，性能良好，结果准确。The application of artificial neural network\|spectrophotometry in simultaneously determinating multi\|component of Zengxiao Lianhuang Tablet is described in this paper. The proposed method is used for determination of three components (SD,SMZ,TMP) and their average recoveries are 103.1% (SD) , 98.21% (SMZ) and 98.76% (TMP) respectively. The effect of the network parameters on the analytical results are dicussed .The results show that the method is accurate and the network performs satifactorily.

关 键 词：测定 磺胺嘧啶 磺胺甲基异恶唑 甲氧苄胺嘧啶 

分 类 号：R978.2[医药卫生—药品]