荧光各向异性法研究酸度对四磺基铝酞菁与牛血清白蛋白相互作用的影响  被引量:10

Investigation of the Association Between Bovine Serum Albumin(BSA) and Aluminum Tetrasulfonated Phthalocyanine(AlS_4Pc) by Fluorescence Anisotropy

在线阅读下载全文

作  者:李东辉[1] 彭兴跃[2] 叶东 许金钩[3] 

机构地区:[1]厦门大学抗癌研究中心生物系 [2]厦门大学抗癌研究中心化学系 [3]厦门大学抗癌研究中心教育部生命过程与材料分析科学开放研究实验室,厦门361005

出  处:《高等学校化学学报》1999年第8期1218-1220,共3页Chemical Journal of Chinese Universities

基  金:国家自然科学基金! (批准号 :2 9775 0 2 1)资助

摘  要:Fluorescence anisotropy was employed for the investigation of the association between AlS 4Pc and BSA. The average binding number of AlS 4Pc to BSA was calculated and the constants of association reaction occurring in the medium of pH 7 0 were shown. The results revealed that the interaction between AlS 4Pc and BSA was strong, which implied that AlS 4Pc may be stored and transferred by serum albumin. The merits of the method used were also pointed out.Fluorescence anisotropy was employed for the investigation of the association between AlS 4Pc and BSA. The average binding number of AlS 4Pc to BSA was calculated and the constants of association reaction occurring in the medium of pH 7 0 were shown. The results revealed that the interaction between AlS 4Pc and BSA was strong, which implied that AlS 4Pc may be stored and transferred by serum albumin. The merits of the method used were also pointed out.

关 键 词:四磺基铝酞菁 酞菁 酸度 荧光各向异性 白蛋白 

分 类 号:O627.31[理学—有机化学] Q512.104[理学—化学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象