儿童抗氧化维生素摄入水平与抗氧化能力关系  

Effect of dietary antioxidant vitamin intake on anti-oxidative capacity in school-age children

作　　者：唐咏梅[1] 周会[1] 刘毅[1] 李云[1] 宁鸿珍[1] 周瑞华[1] 王茜[1] 

机构地区：[1]华北煤炭医学院预防医学系,河北省煤矿卫生与安全实验室,河北唐山063000

出　　处：《中国公共卫生》2011年第4期412-414,共3页Chinese Journal of Public Health

基　　金：河北省医学科学研究重点课题计划资助项目(08178)

摘　　要：目的探讨膳食抗氧化维生素摄入对儿童抗氧化能力影响。方法选择河北省唐山市3所小学382名1～6年级学生进行一般情况、食物摄取频率和膳食调查,经家长知情同意后采静脉血测定其血清维生素、抗氧化酶和过氧化产物水平;采用营养计算器V1.6转换数据,SPSS11.5软件进行分析。结果当维生素A(VA)摄入水平>60%且≤80%推荐摄入量(RNI)时,血清VA、丙二醛(MDA)分别为(267.30±80.77)μg/L和(2.52±0.48)μmol/L,与参考值比较,差异均有统计学意义(P<0.05);当类胡萝卜素摄入量<440μg视黄醇当量(RE)时,血清VA低于参考值,MDA高于参考值;<260μg RE时,血清β-胡萝卜素低于参考值;当维生素C(VC)摄入水平分别<100%RNI和<120%RNI时,血清VC、谷胱甘肽过氧化物酶(GSH-Px)<参考值,<140%RNI时,MDA高于参考值;当维生素E(VE)摄入水平<100%适宜摄入量(AI)时,血清VE水平<参考值;<120%AI时,超氧化物歧化酶(SOD)低于参考值,MDA水平高于参考值。结论当VA摄入量≥80%RNI、类胡萝卜素摄入量≥440μg RE、VC摄入量≥140%RNI、VE摄入量≥120%AI时,儿童体内抗氧化指标水平达到正常。Objective To study the effect of vitamin A,C,E intake on antioxidant capacity in children. Methods Totally 382 students of 1-6 grades from 3 primary schools were investigated on general state of health,5 days diet and 1 month food frequency.Serum vitamin,antioxidant enzymes and peroxidation product were determined after informed the consent to their parents.The intakes were transformed with nutrition calculator V1.6.The data were analyzed with SPSS11.5 software. Results When vitamin A intake was less than 80% and more than 60% of the reference nutrient intake（RNI）,the level of serum vitamin A was lower than normal level and malondialdehyde（MDA） was higher than normal level.When carotenoids intake was less than 440μg retinal equivalent（RE）,the level of serum vitamin A was lower than normal level and MDA was higher than normal level.When carotenoids intake was less than 260μg RE,serum beta-carotene was higher than normal level.When vitamin C intake was less than 100% of RNI or 120% of RNI,serum vitamin C and glutathione peroxidase（GSH-Px） were lower than the normal.When vitamin C intake was less than 140% of RNI,MDA was higher than normal level.When vitamin E intake was less than 100% of adequate intake（AI）,the level of serum vitamin E was lower than normal level.When vitamin E intake was less than 120% of RNI,superoxide dismutase（SOD） was under normal level and MDA was higher than normal level. Conclusion Children＇s antioxidant capacity are normal when their intakes of vitamin A80% of RNI,carotenoids440μg RE,vitamin C140% of RNI,and vitamin E120% of AI.

关 键 词：学龄儿童 维生素 摄入量 抗氧化 回归分析 

分 类 号：R114[医药卫生—卫生毒理学]