连续性血液净化治疗脓毒症所致高钠血症41例效果观察  

Effect observation on the hypernatremia in 41 patients with sepsis treated by continuous blood purification

作　　者：吴英凤[1,2] 马洪俊[2] 曹书华[3] 

机构地区：[1]天津医科大学,天津300280 [2]天津市大港油田总医院 [3]天津市第一中心医院

出　　处：《山东医药》2011年第11期39-40,共2页Shandong Medical Journal

摘　　要：目的观察连续性血液净化治疗脓毒症所致高钠血症的临床疗效。方法将65例脓毒症所致高钠血症患者按照治疗方法分为观察组41例及对照组24例,两组均予脓毒症的相关治疗,观察组在此基础上采用连续性血液净化(CBP)治疗,对照组采取胃肠道补水的传统方法治疗,观察两组治疗前、后血钠(Na)、血尿素氮、血肌酐及血浆渗透压变化,比较其高钠治愈率和病死率。结果观察组治疗后血Na、血浆渗透压、病死率均明显低于对照组,治愈率明显高于对照组,P<0.05;其余各指标比较无统计学差异。结论 CBP治疗高钠血症效果显著,能明显改善患者预后;优于胃肠道补水的传统治疗方法。Objective The observe the clinical effect of hypernatremia in patients with sepsis treated by the continuous blood purification（CBP）.Methods Based on different treatment models,65 patients were divided into two groups,one is the observed group for 41 cases and the other is the control group for 24 cases.All patients of two groups have the treatment of sepsis,on the basis of these treatment,the observed group was given the treatment of CBP,the observed group was given the conditional treatment-water replenishing through gastrointestinal tract.The serum natrium,BUN,SCr,crystal osmotic pressure were observed before and after the treatment,the recovery rate and fatality rate were also evaluated.Results The values of serum natrium,crystal osmotic pressure and the fatality rate in the observed group were lower than those in the control group,and the recovery rate was higher,P〈0.05;the other datas had no statistical difference.Conclusions Treat hypernatremia by CBP has satisfactory effect,can improve the patients′ prognosis.CBP is superior to the conditional treatment-water replenishing through gastrointestinal tract.

关 键 词：高钠血症 连续性血液净化 脓毒症 

分 类 号：R459.7[医药卫生—急诊医学]