乳腺肿块的直径和深度对最大血红蛋白浓度测量的影响  

Influence of Diameter and Depth of Breast Mass on Maximum Hemoglobin Concentration Detected by US-guided Optical Imaging System

作　　者：赵天慧[1] 张炽敏[2] 李嘉[2] 

机构地区：[1]东南大学附属第二医院超声诊断科,南京市21003 [2]东南大学附属中大医院超声诊断科

出　　处：《中国超声医学杂志》2011年第3期217-220,共4页Chinese Journal of Ultrasound in Medicine

基　　金：江苏省卫生厅资助课题(No.H200756)

摘　　要：目的阐明乳腺肿块的直径和深度对超声光散射系统最大血红蛋白浓度(maximum hemoglobin concentration,MHC)测定的影响程度和规律。方法制备不同直径(5、10、15、20、25 mm)的含血球囊(血红蛋白浓度分别为50、100、200、400μmol/L),用超声光散射成像系统测定在不同深度(5、10、15、20、25 mm)条件下含血球囊的MHC值,用Excel软件分析球囊直径和深度与MHC之间的关系。结果 (1)在球囊深度和血红蛋白浓度恒定的条件下,MHC随着球囊直径的增大呈线性升高,MHC=a×球囊直径+b,ab均为常数,下同;(2)在球囊直径和血红蛋白浓度恒定的条件下,MHC随着球囊深度的增加呈线性降低,MHC=a×球囊深度+b。结论乳腺肿块的大小和深度影响超声光散射成像系统MHC的测定。Objective To investigate the influence degree and law of diameter and depth of breast mass on maximum hemoglobin concentration （MHC） detected by ultrasound-guided diffuse optical imaging system （UDOIS）. Methods The sacculi of different diameter（5,10,15,20,25 mm）in the container filled with 0.6% intralipid emulsion were detected by UDOIS at different depth（5,10,15,20,25 mm）. The hemoglobin concentration of these sacculi was 50,100,200 and 400 μmol/L, respectively. The relationship between diameter or depth of sacculus and MHC was analysed by Excel software. Results （1）When the depth and the hemoglobin concentration of sacculi were fixed,MHC in- creased linearly with the augment of saeculi diameter（MHC=a×sacculus diameter＋b）. （2）When the diameter and the hemoglobin concentration of sacculi were fixed, MHC decreased linearly with the augment of sacculi depth（MHC= a× sacculus depth＋b）. Conclusions The diameter or the depth of breast mass impacts on the detection of MHC.

关 键 词：超声光散射 最大血红蛋白浓度 乳腺肿块 直径 深度 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]