2009-2010年山西省流感／甲型H1N1流感的病原学监测分析  

Analysis on the etiological surveillance of influenza/novel influenza A （ H1N1 ） from 2009--2010 in Shanxi province

作　　者：任斌知[1] 王乃昌[1] 冯军军[1] 赵嵘[1] 张凡非[1] 

机构地区：[1]山西省疾病预防控制中心,太原030012

出　　处：《中华实验和临床病毒学杂志》2011年第1期20-22,共3页Chinese Journal of Experimental and Clinical Virology

基　　金：基金项目：08年度留学回国人员科技活动项目择优资助（启动类）;山西省卫生厅科技攻关项目（200848）

摘　　要：目的分析掌握山西省2009--2010年流感／甲型H1N1流感的流行特征，为预测和防控流感／甲型H1N1流感流行提供科学依据。方法对哨点医院和集体发热疫情进行监测采样，采用病毒核酸检测法和细胞培养法分离鉴定流感／甲型H1N1流感病毒，并对2009年5月至2010年4月山西省录入“中国流感监测信息系统”的流感样病例监测报告数据及其样本病原学监测数据进行统计分析。结果山西省全年均有流感病毒活动，2009年流行优势毒株为甲型H1N1流感病毒，流行最高峰在11月（阳性率为58．1％，甲型H1N1占88．1％），主要导致59岁以下人群发病，其中5-24岁年龄组阳性率较高，进入2010年后乙型（Victoria系）流感病毒的活动有所增加，成为流行株。结论流感样病例监测和病原学监测，可以及时反映流感活动状况，对于掌握该省流感／甲型H1N1流感流行规律有着重要意义。Objective To study the epidemical characteristics of influenza/novel influenza A （H1N1） in Shanxi province from 2009 to 2010, and to provide scientific foundations for predicting and controlling the pandemic outbreak of influenza/novel influenza A （H1N1） effectively. Methods All samples were collected from, cases that resemble influenza cases in sentinel hospital and influenza outbreak. The influenza were detected by PCR and isolated by MDCK cell culture method. Finally, Shanxi province surveillance data from May, 2009 to April, 2010 of influenza like illness （ILI） cases and pathogen detections were analyzed. Results In Shanxi province, influenza viruses kept activation in Whole year. The predominant pandemic strain in 2009 was novel influenza A（ H1N1 ） virus. The strong peak was around November, 2009 [ positive rate： 58.1% , novel influenza A （ H1N1 ） of the total： 88.1% ]. As well, the people infected influenza caused by novel influenza A （H1N1） were mainly under 59-year-old, and the higher positive rates were concentrated in the people from 5-year-old to 24-year-old. In 2010, influenza B （Victoria） viruses were mainly detected from clinical specimens and became the dominant strain. Conclusion： Surveillance of Influenza liue illnes, （ILI） and etiology, which can promptly reflect the influenza epidemic situation, play a significant role for understanding epidemic rule of influenza/novel influenza A（ H1N1 ）.

关 键 词：流感病毒A型 人 流感 逆转录聚合酶链反应 

分 类 号：R511.7[医药卫生—内科学]