邻苯二甲酰胺类化合物的合成及杀虫活性  

Synthesis and Insecticidal Activities of Phthalic Diamides

作　　者：韦伟[1] 朱冰春[1,2] 邢家华[2] 孔小林[2] 谭成侠[1] 李小年[1] 

机构地区：[1]浙江工业大学化学工程与材料学院,杭州310014 [2]浙江省化工研究院国家南方农药创制中心浙江基地,杭州310023

出　　处：《农药》2011年第4期249-252,共4页Agrochemicals

基　　金：中国博士后科学基金面上资助项目(20090451487);浙江省科技厅省属科研院所专项(2010F20009)

摘　　要：[方法]以含取代基的邻苯二甲酸酐、2-氨基-2-甲基丙腈和全氟异丙基苯胺为起始原料,合成了13个未见文献报道的新型邻苯二甲酰胺类化合物。[结果]通过1H NMR、IR和MS确定了化合物的结构,并进行了生物活性测试。其中化合物6a在0.8 mg/L质量浓度下对小菜蛾、棉铃虫和草地贪夜蛾的致死率分别为90%、100%和75%;0.16 mg/L质量浓度下对棉铃虫和草地贪夜蛾的致死率分别为55%和50%。[结论]此类新型的邻苯二甲酰胺类化合物对鳞翅目害虫具有较好的杀虫活性。[Methods] 13 Novel phthalic diamides were synthesized from substituted phthalic anhydride,2-amino-2-methylpropionitrile and heptafluoroisopropyl aniline.[Results] The chemical structures of the target compounds were confirmed by 1h Nmr,ir and ms.And the biological activities of the target compounds were tested.The control effect of compounds 6a against Plutella xylostella,helicoverpa armigera hubner and spodoptera frugiperda were 90,100 and 75% at the concentration of 0.8 mg/l,against helicoverpa armigera hubner and spodoptera frugiperda were 55 and 50% at the concentration of 0.16 mg/l,respectively.[Conclusions] These novel phthalic diamides showed high insecticidal activities against lepidopterous pests.

关 键 词：邻苯二甲酰胺 全氟异丙基苯胺 合成 杀虫活性 

分 类 号：TQ453.2[化学工程—农药化工]