自血疗法配合地氯雷他定、肤疾宁治疗结节性痒疹临床观察  

Clinical Observation of Prurigo Nodularis Treated with Autohemotherapy Combined with Desloratadine and Triamcinolone-Acetonide-Neomycin Paste

作　　者：郑慕雄 李瑾娴 许敏鸿 

机构地区：[1]广东汕头市皮肤医院,广东汕头515041

出　　处：《世界中西医结合杂志》2011年第3期215-216,219,共3页World Journal of Integrated Traditional and Western Medicine

摘　　要：目的观察自血疗法配合口服地氯雷他定、肤疾宁治疗结节性痒疹的临床疗效及复发率。方法将80例患者随机分为两组,治疗组40例采用自血疗法配合口服地氯雷他定片、外用肤疾宁贴膏治疗;对照组40例采用口服地氯雷他定片、外用肤疾宁贴膏治疗;疗程均为30 d。结果治疗组痊愈15例,有效率82.05%;对照组痊愈9例,有效率58.97%,两组有效率比较,差异有统计学意义(P<0.05);治疗结束30 d后随访有效病例,治疗组复发8例,总复发率25.00%;对照组复发13例,总复发率56.52%,两组总复发率比较,差异有统计学意义(P<0.05)。结论采用自血疗法配合地氯雷他定、肤疾宁治疗结节性痒疹,能降低复发率,临床疗效明显优于单纯采用口服地氯雷他定片、外用肤疾宁贴膏,值得临床推广运用。Objective To observe the clinical efficacy and recurrence rate of prurigo nodularis treated with autohemotherapy combined with oral administration of desloratadine as well as triamcinolone-acetonide-neomycin paste.Methods 80 cases were randomized into two groups.In a treatment（40 cases）,autohemotherapy was adopted together with oral administration of desloratadine and topical application of triamcinolone-acetonide-neomycin paste.In a control group（40 cases）,oral administration of desloratadine and topical application of triamcinolone-acetonide-neomycin paste were applied.The duration of treatment was 30 days in either group.Results 15 cases were cured in treatment group and the effective rate was 82.05%.9 cases were cured in control group and the effective rate was 58.97%.The difference was significant statistically in comparison of the effective rate between two groups（P0.05）.The follow-up was conducted for the effective cases 30 days later after treatment.8 cases were recurred in treatment group and the total recurrence rate was 25.00%.13 cases were recurred in control group and the total recurrence rate was 56.52%.The difference was significant statistically in comparison of the total recurrence rate between two groups（P0.05）.Conclusion Autohemotherapy combined with desloratadine and triamcinolone-acetonide-neomycin paste reduces the recurrence rate of prurigo nodularis and the clinical efficacy is superior apparently to simple oral administration of desloratadine and topical application of triamcinolone-acetonide-neomycin paste.Thus,this therapy deserves to be promoted in practice.

关 键 词：自血疗法 地氯雷他定 肤疾宁 结节性痒疹 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]