132例临床真菌感染的病原学及流行病学分析  

The Etiology and Epidemiology Analysis of 132 Cases of Clinical Fungal Infection

作　　者：王长嘉[1] 隋达伟[2] 贺丹[3] 钱永清[3] 杨慧[3] 崔岩[3] 王丽[3] 

机构地区：[1]吉林省人民医院肝病科,吉林长春130021 [2]长春市中心医院检验科,吉林长春130051 [3]吉林大学白求恩医学院病原生物学系,吉林长春130021

出　　处：《中国实验诊断学》2011年第3期418-420,共3页Chinese Journal of Laboratory Diagnosis

基　　金：国家自然科学基金重大国际合作资助项目(30910103903);吉林省科技发展计划重点资助项目(20080444-2)

摘　　要：目的了解长春市中心医院1年间住院患者真菌感染现状及流行病学特征,为临床真菌感染的诊断、治疗提供参考。方法收集临床呼吸科、老年病科等真菌感染患者的痰、尿等标本,进行病原真菌的分离、鉴定,并分析流行病学特征。结果收集132份临床标本,主要来源于呼吸科(55.3%),以痰标本为主(96.2%)。共分离获得假丝酵母133株,其中白假丝酵母最多(66.2%),其次为热带假丝酵母(20.3%)。结论与其他科室相比,该医院呼吸道疾病患者发生真菌感染最多,以白假丝酵母为主。应高度重视院内真菌感染,积极开展病原学监测,以减少感染的机会。Objective To investigate the condition and the epidemiological characteristics of fungal infection of patients in one year at Central Hospital of Changchun City,and provide evidence of clinical diagnosis and treatment of fungal infection.Methods The samples of sputum,urine and other specimens were taken from clinical patients in Department of Respiratory,Geriatrics and others.Pathogenic fungi were isolated and identified,and the epidemiological characteristics were analyzed.Results A total of 132 samples were collected in this study.Among them,55.3% of the samples were from Department of Respiratory and 96.2% were sputum.133 strains of Candia were isolated,66.2% of them belonged to Candida albicans and 20.3% to Candida tropicalis.Conclusion In this hospital,patients with respiratory diseases were most susceptible to fungal infection compare with other department,and Candida albicans was the main pathogen.In order to decrease fungal infection,more attention should be paid to the nosocomial infection,and it is important to actively develop the etiology monitoring.

关 键 词：真菌感染 流行病学 鉴定 

分 类 号：R181.3[医药卫生—流行病学] R519[医药卫生—公共卫生与预防医学]