2016例可疑糖尿病患者糖耐量检测结果分析  

Analysis of 2 016 Cases OGTT Results from Suspect Diabetic Patients

作　　者：刘春燕[1] 徐大正 胡宪蕴 张楷 李梅[1] 李军[1] 冯凭[1] 邱明才[1] 王维力[1] 王家驰[1] 高玉琪[1] 尹潍[1] 

机构地区：[1]天津医科大学总医院,300052 [2]开滦矿务局赵各庄医院 [3]天津市天和医院特检中心

出　　处：《天津医药》1999年第8期472-474,共3页Tianjin Medical Journal

摘　　要：探讨糖尿病（ＤＭ）空腹血糖（ＦＰＧ）诊断标准，以及口服葡萄糖耐量试验（ＯＧＴＴ）在ＤＭ诊断中的价值。方法：２ ０１６例可疑糖尿病受试者均接受 ＯＧＴＴ试验。以服糖后 ３０或 ６０和 １２０分的血糖均≥１１．１ｍｍｏｌ／Ｌ作为诊断ＤＭ的标准。按 ＦＰＧ分别≥７．８、７．０、６．７、６．１、５．６和 ５．０ ｍｍｏｌ／Ｌ由计算机进行分组统计。结果：ＦＰＧ≥７．８ ｍｍｏｌ／Ｌ的 ＤＭ检出率为 ７８．０９％（１０４８例／１ ３４２例），漏诊率为２１．９１％（２９４例／１ ３４２例），误诊率为３．１％（３３例／１ ０８１例）；ＦＰ≥７．０ ｍｍｏｌ／Ｌ的 ＤＭ检出率为 ８６．９％（１１６７例／１ ３４２例），漏诊率为 １３．０％（１７５例／１ ３４２例），误诊率５．６％（６９例／１ ２３６例）；ＦＰＧ≥６．１ｍｍｏｌ／Ｌ的ＤＭ检出率为９４．７％（１２７１例／１ ３４２例），漏诊率５．３％（７１例／１ ３４２例），误诊率１０．８％（１５４例／１ ４２５例）。直线相关分析表明 ＦＰＧ与服糖后 １２０分的血糖水平呈正相关（ｒ＝０．８６３ ９，Ｐ＜０．０００１）。当ＦＰＧ≥６．１ｍｍｏｌ／Ｌ时服糖后１２０分血糖为１１．０６ ｍｍｏｌ／Ｌ（１９９．０Exploring the diagnostic criteria of fasting plasma glucose (FPG) in diabetic population, evaluating the value of oral glucose tolerance test (OGTT) in the diagnosis of diabetes mellitus (DM). Methods: 2 016 cases all received 75g OGTT, taking plasma glucose level≥11. 1 mmol/L at 30 or 60 and 120 minutes as the diagnostic criterion of DM. The data were statisticed by computer according the FPG≥7 .8, 7.0, 6.7, 6.1, 5. 6 and 5. 0 mmol/L respectively. Results: When FPG≥7. 8 mmol/L detectable rate of DM was 78 .09 % (1048 cases/1 342 cases),missed diagnosis rate was 21.91 % (294 cases/1 342 cases), misdiagnosis rate was 3. 1 % (33 cases/1 081 cases), when FPG≥7. 0 mmol/L, detectable rate of DM was 86.9% (1167 cases/1342 cases), missed diagnosis rate was 13.0% (175 cases/1342 cases),misdiagnosis rate was 5 .6% (69 cases/1236 cases), when FPG≥6. 1 mmol/L,detectable rate of DM was 94 .7% (1271 cases/1 342 cases),missed diagnosis rate was 5. 3 % (71 cases/1 342 cases),misdiagnosis rate was 10 .8% (154 cases/1425 cases). The results of linear regression analysis indicated that FPG corresponded to PG 120 min positively(r = 0. 863 9, P < 0. 000 1 ). While FPG ≥6. 1 mmol/L,PG 120 min was 11 .06 mmol/L(199.0 mg/d1), it was most close to 11. 1 mmol/L(200 mg/d1). Moreover,diabetic patients who had FPG<5 .0 mmol/L consisted of 0.7% (10 cases/1 342 cases) in all DM patients. Conclusion: (1)FPG≥6. 1 mmol/L should be regarded as one of the diagnostic criteria of DM, (2)We can not take the FPG as the only diagnostic standard otherwise some diabetic patients might be missed. OGTT has unreplaceable role in the early diagnosis of DM.

关 键 词：糖尿病 葡糖耐量试验 血糖 

分 类 号：R587.104[医药卫生—内分泌]