武汉地区庚型肝炎病毒感染的血清流行病学调查  

The Prevalence of Hepatitis G Infection in Wuhan Area

作　　者：田德英[1] 宋佩辉[1] 夏宁邵[1] 虞涤霞[1] 张振纲[1] 杨道锋[1] 黄元成[1] 魏镜龙[1] 雷红波 

机构地区：[1]同济医科大学附属同济医院传染科,武汉430030

出　　处：《同济医科大学学报》1999年第4期347-349,共3页Acta Universitatis Medicinae Tongji

基　　金：国家863课题资助

摘　　要：为了解武汉地区庚型肝炎病毒 （ＨＧＶ） 感染状况， 采用酶联免疫试验 （ＥＬＩＳＡ） 和逆转录聚合酶链反应（ＲＴ－ＰＣＲ） 检测１４２６例， １６ 种不同人群血清中抗－ＨＧＶ、ＨＧＶ－ＲＮＡ。结果显示ＨＧＶ的感染率为９．８％ （１４０／１４２６），１６种人群中ＨＧＶ感染率的高低依次为病毒性肝炎（１５．９５％ ）、卖淫吸毒者（１４．４３％ ）、血液透析患者（１３．１１％ ）、血液病（１１．７％ ）、静脉吸毒者（９．１％ ）， 提示各类型肝病人群均有ＨＧＶ感染的重要途径， ＨＧＶ也可经性途径传播， 血液病。To investigate the prevalance of HGV in Wuhan area, ELISA and RT PCR were employed to detect sera anti HGV and HGV RNA in 1426 cases who were diveded into 16 groups. The results showed that infection rate of HGV in all cases was 9 8% (140/1426). The infetion rates of HGV in patients with viral hepatitis, hemodialysis and hemopathy were 15 95%, 13 11% and 11 7% respectively. The infection rate of women who prostituted and drug addicted simultaneously was 14 43% and other i.v. drug users was 9 1%. The results suggest that the population with various hepatic diseases have a vital approach for HGV infection. HGV can be transferred from sexual route. The patients with hemopathy or hemodialysis are the high risk population for HGV infection.

关 键 词：庚型肝炎病毒 流行病学 ELISA RT-PCR 

分 类 号：R512.63[医药卫生—内科学] R373.2[医药卫生—临床医学]