瓦布贝母中一瓦布碱的2D NMR研究  

2D NMR STUDIES ON AN WABUENINE FROM FRITILLARIA WABUENSIS

作　　者：苏甫[1] 王化远[1] 

机构地区：[1]华西医科大学药学院,成都610041

出　　处：《波谱学杂志》1999年第4期353-358,共6页Chinese Journal of Magnetic Resonance

摘　　要：从四川产家种贝母新种———瓦布贝母（Ｂｕｌｂｕｓ Ｆｒｉｔｉｌｌａｒｉａ Ｗａｂｕｅｎｓｉｓ Ｓ．Ｙ．Ｔａｎｇ ｅｔ Ｓ．Ｃ．Ｙｕｅｈ） 鳞茎中分离出一生物碱．经采用ＤＥＰＴ、１Ｈ－ １ＨＣＯＳＹ、１３Ｃ－ １ＨＣＯＳＹ ＭＭＲ 等多种技术对化学结构及构型进行了研究，确证该生物碱为西贝素β氮氧化物（ｉｍｐｅｒｉａｌｉｎｅβＮＯｘｉｄｅ） ．The alkaloids were isolated from the bulb of Fritillaria wabuensis S.Y.Tang et S.C. Yueh the best “Chuan Bei” cultivated in Sichuan Province, the structure and conformation of an alkaloid was studied and determined as imperialine β N Oxide by \{\}\+1H-\+1H COSY, \{\}\+\{13\}C-\+1H COSY 2D nuclear magnetic resonance technique, In this paper, we report the detailed research of very rare imperialine β N Oxides in nature using NOESY,HMQC and HMBC 2D NMR new technique.

关 键 词：瓦布贝母 西贝素 2DNMR 生物碱 

分 类 号：R284[医药卫生—中药学]