血铅超标工人两种驱铅治疗方案疗效初步研究  

Observation on the effect of two therapeutic schemes for treatment of workers with excessive levels of blood lead

作　　者：温贤忠[1,2] 刘移民[3,2] 蒋琴琴[2] 

机构地区：[1]广东省职业病防治院,广东广州510030 [2]中山大学公共卫生学院,广东广州510080 [3]广州市职业病防治院,广东广州510620

出　　处：《中国热带医学》2011年第4期485-487,共3页China Tropical Medicine

摘　　要：目的比较依地酸二钠钙肌肉注射和静脉滴注两种驱铅治疗方案的疗效差异,为驱铅治疗研究提供科学数据。方法采用回顾性队列研究,选择治愈的273例工人为研究对象,以疗程、住院天数和第1疗程第1d尿铅排量为判断疗效的指标,比较依地酸二钠钙肌肉注射和静脉滴注的疗效差异。结果静脉滴注组治疗效果优于肌肉注射组,表现为可缩短住院疗程和住院天数,症状、体征改善好,尿铅排出量明显高于肌肉注射组。结论血铅超标工人驱铅治疗建议采用依地酸二钠钙静脉滴注治疗方案。Aim To compare the therapeutic effects of the two commonly used lead-eliminating methods on workers with higher blood lead levels. Methods The calcium disodium EDTA intramuscular injection and calcium disodium EDTA intravenous drip were used to treat workers with excessive levels of lead in blood. There 273 cured workers were chosen as controls. The results of lead elimination was recorded based on the therapeutic course, days of hospitalization, amount of urine lead elimination and referenced by the changes of symptoms. Results The therapeutic effects of drip group was better than the intramuscular injection group. Comapred to the intramuscular goup the therapeutic course in the intravenous drip group was shorter,the days of hospitalization was less,the amount of urine lead elimination was higher and symptoms an signs were improved aparendy. Conclusion It is suggested that calcium disodium EDTA intravenous drip be used for lead elimination treatment of workers with highe levels of lead in blood.

关 键 词：血铅:治疗方案 驱铅效果 

分 类 号：R181[医药卫生—流行病学]