2例危重症甲型H1N1流感患者医院获得性肺炎病原菌分析及治疗对策  

Pathogenic bacteria causing hospital-acquired pneumonia in 2 cases of patients with critical influenza A(H1N1) and countermeasures for treatment

作　　者：罗晓斌[1] 蒋远明[1] 汪翼[1] 

机构地区：[1]遂宁市中心医院,四川遂宁629000

出　　处：《中华医院感染学杂志》2011年第7期1355-1356,共2页Chinese Journal of Nosocomiology

摘　　要：目的探讨危重症甲型H1N1流感患者医院获得性肺炎的病原菌种类及治疗对策。方法对2010年2月医院成功救治的2例危重症甲型H1N1流感患者病例资料进行回顾性分析。结果 2例患者多次痰标本培养出嗜麦芽寡养单胞菌、鲍氏不动杆菌及铜绿假单胞菌,为多药耐药或泛耐药菌,多药耐药菌均对头孢哌酮/舒巴坦敏感,对于泛耐药菌加大头孢哌酮/舒巴坦剂量并联合喹诺酮类和氨基糖苷类抗菌药物,亦能取得良好效果;2例患者均治愈出院,随诊情况良好。结论危重症甲型H1N1流感患者易发生医院获得性肺炎,以大剂量头孢哌酮/舒巴坦联合氟喹诺酮类和氨基糖苷类抗菌药物治疗有效。OBJECTIVE To study species of pathogenic germs and countermeasure of HAP to critical influenza A(H1N1).METHODS The database of 2 critical influenza H1N1 in our hospital in Feb 2010 was seudied retrospectively.RESULTS There were 2 patients with multiple sputum samples cultivate eosinophilic malt narrow food,Acinetobacter baumannii and Pseudomonas aeruginosa,with MDR,or PDR bacteria.The MDR bacteria was sensitive to cefoperazone sulbactam.TO PDR bacteria,increased dose of cefoperazone sulbactam and joint fluoroquinolones and aminoglycoside antibiotics could achieve good results.CONCLUSION Critical H1N1 influenza patients are vulnerable to hospital-acquired pneumonia,large doses of cefoperazone sulbactam jointing with fluoroquinolones and aminoglycoside antibiotics can effectively treat.

关 键 词：危重症 甲型H1N1流感 医院获得性肺炎 病原菌 治疗 

分 类 号：R181.32[医药卫生—流行病学]