早期呼吸支持和轻度低温治疗在重型颅脑损伤术后的应用  

Clinical effect of early mechanical ventilation combined with mild hypothermia on severe traumatic brain injury after decompressive craniectomy

作　　者：陈汉民[1] 廖圣芳[1] 余锦刚[1] 

机构地区：[1]解放军第180医院神经外科,福建泉州362000

出　　处：《中国现代医学杂志》2011年第7期860-861,864,共3页China Journal of Modern Medicine

摘　　要：目的探讨早期呼吸支持和轻度低温在重型颅脑损伤去骨瓣减压术后患者的治疗作用。方法 62例重型颅脑损伤去骨瓣减压术后患者分成治疗组和对照组,治疗组早期进行呼吸支持及轻度低温治疗,对照组高热者使用降温毯降温、呼吸衰竭者进行机械通气。结果两组病例术后第72小时颅内压比较,P<0.01;死亡率比较,P<0.05;两组间肺部感染率比较,P>0.05。结论重型颅脑损伤后早期进行呼吸支持和轻度低温治疗具有较好的治疗作用。【Objective】 To investigate the effect of early mechanical ventilation combined with mild hypothermia on the patients with severe traumatic brain injury after decompressive craniectomy.【Methods】 62 cases with severe traumatic brain injury after decompressive craniectomy were randomly divided into two groups： treatment group（n =32）and control group（n =30）.In treatment group,all patients received early mechanical ventilation combined with mild hypothermia.In control group,only patients with high fever used hypothermic blanket and using mechanical ventilation when respiratory failure occurred.【Results】 After 72 hours,there was significant difference between two groups in intracranial pressure（P 0.01） and death rate（P 0.05）,there was no significant difference in the rate of pulmonary infection（P 0.05）.【Conclusion】 Early mechanical ventilation combined with mild hypothermia is a effective means for patients with severe traumatic brain injury after decompressive craniectomy.

关 键 词：重型颅脑损伤 骨瓣减压 轻度低温 机械通气 

分 类 号：R651.15[医药卫生—外科学]