塑料表面载银微凝胶层层组装膜的制备及抗菌活性  

Layer-by-layer Assembled Microgel Films Containing Silver Nanoparticles as Antimicrobial Coatings on Plastics

作　　者：刘峰[1] 王旭[1] 叶开其[1] 裘令瑛 沈家骢[1] 

机构地区：[1]吉林大学超分子结构与材料国家重点实验室,化学学院,长春130012

出　　处：《高等学校化学学报》2011年第4期990-994,共5页Chemical Journal of Chinese Universities

摘　　要：以载银聚烯丙基胺盐酸盐-葡聚糖微凝胶与聚苯乙烯磺酸钠为构筑基元,利用层层组装技术制备了一种可直接沉积在疏水的塑料基底表面的载银抗菌微凝胶膜.研究结果表明,该载银抗菌微凝胶膜具有很好的抗菌能力,并且其抗菌活性可以通过控制载银微凝胶膜的组装层数进行调控.这种沉积在塑料表面的载银抗菌微凝胶膜具有良好的稳定性和基底黏附力,能够保障其长效抗菌性.Antimicrobial coatings on hydrophobic plastic surfaces were directly fabricated by layer-by-layer deposition of cross-linked poly（allylamine hydrochloride） and dextran microgels containing silver nanoparticles（Ag@PAH-D） with poly（sodium 4-styrenesulfonate）（PSS）.The as-prepared Ag@PAH-D/PSS microgel films are effective in prohibiting the growth of Escherichia coli.The antimicrobial activity of the coatings can be easily controlled by tailoring the number of coating deposition cycles.The antimicrobial coatings of Ag@PAH-D/PSS microgel films are stable and have satisfactory adhesion to the underlying plastic substrates,which guarantee the long-term application of the coatings.

关 键 词：层层组装 聚合物微凝胶 抗菌涂层 

分 类 号：O631[理学—高分子化学]