先天性胆总管囊肿患儿血清酶学测定  

DETERMINATION OF SERUM ENZYMES IN CHILDREN WITH HOLEDOCHAL CYST

作　　者：赵莉[1,2] 李振东[1,2] 尹济群[1,2] 李索林[1,2] 李明红[1,2] 陈新英[1,2] 时保军[1,2] 温哲[1,2] 于增文[1,2] 

机构地区：[1]河北医科大学第二医院小儿外科 [2]河北医科大学第二医院检验科

出　　处：《河北医科大学学报》1999年第5期279-281,共3页Journal of Hebei Medical University

摘　　要：目的了解胆总管囊肿对肝脏功能的影响。方法对２５例胆总管囊肿患儿进行术前、术后检测各种血清酶（ＡＬＰ、ＧＧＴ、ＡＬＴ、ＡＳＴ、ＡｃｈＥ、ＭＡＯ等）以及肌酐、胆固醇等反映肝脏功能的指标。并进行术前、术后分组比较。结果黄疸组的ＡＬＰ、ＧＧＴ、ＡＳＴ、ＡＬＴ均明显高于无黄疸组（Ｐ＜０．００５）。而且术后明显低于术前。肝纤维组织增生组ＭＡＯ亦无明显增高。ＡｃｈＥ、肌酐、总蛋白、胆固醇等几项指标均在正常参考值范围。结论胆总管囊肿可以引起肝脏功能损害，主要是由于胆道梗阻胆汁淤滞所致。梗阻越重，时间越长，肝脏损害越重，从酶学改变来看，胆总管囊肿所致肝脏功能损害，在解除胆道梗阻后可以恢复。ObjectiveTo explore the effects of choledochal cyst on liver function.MethodsSerum enzymes level including GGT,ALP,AST,ALT,AchE,MAO etc.were analysed in 25 patients with choledochal cyst.ResultsThe serum GGT,ALT,AST,ALP levels were significantly elevated in the patients with jaundice than that without jaundice.These parameters of the patients with jaundice were significantly decreased after opreation.MAO level was normal in the series.ConclusionCholedochal cyst leads to the injury of liver functioin in different degree.This injury is mainly caused by biliary obstruction and may recover after the biliary obstruction is relieved by operation.

关 键 词：胆总管囊肿 外科手术 血清酶学 测定 儿童 

分 类 号：R726.574[医药卫生—儿科]