99mTc标记红细胞放射核素显像在眼眶肿瘤鉴别诊断中的应用  

99mTc-labeled RBC scintigraphy on diagnosis and differential diagnosis of orbital tumors

作　　者：张虹[1] 丁莹[1] 张遵诚[2] 董华[2] 宋国祥[1] 

机构地区：[1]天津医科大学第二医院眼科天津市眼眶病研究所,天津300211 [2]天津医科大学第二医院眼核医学科,天津300211

出　　处：《中国实用眼科杂志》2010年第12期1329-1331,共3页Chinese Journal of Practical Ophthalmology

基　　金：基金项目：天津市高等学校科技发展基金计划资助项目（编号20060117）：天津市卫生局科技基金项目（编号06K233）

摘　　要：目的 对眼眶肿瘤患者进行99mTc-RBC放射核素显像,根据显像结果对眼眶海绵状血管瘤、血管性疾病和非血管性肿瘤进行诊断和鉴别诊断.方法 经B型超声、CT或MRI等影像学方法证实为眼眶肿瘤的75例患者进行99mTc-RBC放射核素显像,其中男32例,女43例,平均年龄44.7岁.据99mTc-RBC放射核素显像方式不同,做出海绵状血管瘤、血管性疾病、供血丰富肿瘤或其他实体性肿瘤的诊断.所有患者均行手术或活检后经病理组织学诊断.结果 31例海绵状血管瘤显像为血池相开始出现放射性异常浓集影,且随时间推移,1h后放射性浓集影逐渐增强,至4h时晚期延迟相放射核素明显增强;1例海绵状血管瘤各个时相均未见异常放射性浓集影.血管畸形显示为血池相即出现异常的放射性浓集影,30min后逐渐增强,至4h减弱或消失.供血丰富肿瘤显示灌注曲线升高,血池相异常放射性浓集影轻度增强,至延迟相消失或无变化.结论 99mTc-RBC显像可作为诊断和鉴别诊断眼眶海绵状血管瘤、血管性疾病、供血丰富肿瘤及其他实体性肿瘤的一种新方法,为临床选择治疗方法提供依据.Objective To evaluate technetium Tc 99m （99mTc） red blood cell scintigraphy as a new diagnostic tool for diagnosis and differential diagnosis of orbital cavernous hemangioma, vascular diseases and non-vascular tumors on the basis of their vascularization. Methods A total of 75 patients with orbital tumors （32 male and 43 female, averaged age at 44.7 years） demonstrated by B-scan, CT or MRI were performed with 99mTc red blood cell scintigraphy. Orbital cavernous hemangioma, vascular diseases, tumors with rich blood supply and other tumors were diagnosed by their vascularization of scintigraphy. All patients were diagnosed by histopathology. Results Of 31 cases of cavernous hemangioma were positive in early blood pool and as time went by, the positive sign was increased, and the uptake were more dense in delayed blood pool than that in early blood pool. Of 1 case of cavernous hemangioma was negative all the time. Vascular malformation showed abnormal picture in early blood pool and gradually increased 30 minutes later. Tumors with rich blood supply showed increased supply at the beginning, and slightly densed in early blood pool. Conclusions 99mTc red blood cell scintigraphy can be regarded as a new method to differentiate cavernous hemangioma, vascular diseases, tumors with rich blood supply and other tumors. It can provide an evidence for choosing correct treatment methods.

关 键 词：眼眶肿瘤 99mTc-RBC 核素显像 

分 类 号：R817.42[医药卫生—影像医学与核医学]