变应性鼻炎皮下注射和舌下含服特异性免疫治疗依从性对比  

A comparative study of the compliance between subcutaneous immunotherapy and sublingual immunotherapy in patients with allergic rhinitis

作　　者：桂晓钟 陈涌[1] 赵军[1] 程静[1] 

机构地区：[1]安徽省芜湖市第二人民医院耳鼻咽喉科,安徽芜湖241000

出　　处：《中国耳鼻咽喉头颈外科》2010年第12期631-633,共3页Chinese Archives of Otolaryngology-Head and Neck Surgery

基　　金：科技部"十一五"科技支撑计划项目(2007BAI18B15)

摘　　要：目的对变应性鼻炎(AR)患者特异性免疫治疗依从性及其相关影响因素进行分析并提出相应对策。方法对248例AR特异性免疫治疗患者依从性进行分析,并就其与年龄、性别、不同治疗方式以及引起中断治疗的原因进行探讨。结果 AR患者特异性免疫治疗总依从率为60.48%,其中皮下注射为92.19%,舌下含服为49.46%,两者有显著差异(P<0.01);儿童组与成人组依从率,皮下注射分别为97.78%与78.95%,舌下含服分别为90.41%与22.52%,两者有显著差异(P<0.01)。治疗中断原因,对治疗缺乏信心占64.29%,因工作、学习及事务繁忙等因素占25.51%。结论皮下注射患者依从率明显高于舌下含服患者,儿童患者依从率明显高于成人。医护人员指导不力、患者对治疗缺乏信心、自觉疗效不好是中断治疗的主要原因。OBJECTIVE To study the compliance of immunotherapy and related factors in patients with allergic rhinitis.METHODS The treatment compliance of immunotherapy in 248 patients treated in our hospital from June,2008 to June,2010 was analyzed and the factors of age,sex,therapy methods as well as reason for withdrawal were also investigated.RESULTS The overall rate of treatment compliance of immunotherapy was 60.48%.There was a significant difference between the SCIT group and SLIT group（92.19% and 49.46% respectively,P0.01）.Those were also true in children group（SCIT 97.78% and SLIT 90.41% respectively） and adult group（SCIT 78.95% and SLIT 22.52% respectively）（P 0.01）.The common causes for withdrawal were insuficient effectiveness（64.29%）and busy work（25.51%）of the patients.CONCLUSION The treatment compliance rate of SCIT was significantly higher than that of the SLIT and that in children group was also significantly higher than that in adult group.The most common causes for treatment withdrawal were lack of medical guidance and patient＇s doubt about effectiveness.

关 键 词：鼻炎 变应性 常年性 脱敏法 免疫 病人依从 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]