脉搏波时标对臂踝脉搏波传播速度测量的影响  

Influence of Pulse Timing Mark on The Measurement of Brachial-Ankle Pulse Wave Velocity

作　　者：孙欣[1] 赵玉娟[1] 

机构地区：[1]山东大学控制科学与工程学院生物医学工程研究所,济南250061

出　　处：《生物物理学报》2010年第12期1137-1144,共8页Acta Biophysica Sinica

基　　金："863"计划项目(2006AA02Z4D9;2009AA02Z408)~~

摘　　要：臂踝脉搏波传播速度(brachial-ankle pulse wave velocity,baPWV)测量是一种便捷、无创的方法,可用于人体动脉硬化度的评估,在临床和科学研究中广泛应用于血管早期病变的筛查和心血管系统风险的评估。本文设计开发了人体上臂和踝部脉搏波波形采集系统,并利用该系统对59名健康成年人进行实验,研究了目前三种最常用的脉搏波时标(pulse timing mark,PTM)定义方法对baPWV测量的影响。实验结果表明,选用不同的PTM方法所测得的baPWV结果具有显著的差异性(P<0.001)。而且,PTM方法的不同还影响到了baPWV与年龄、血压的相互关系。Brachial-ankle pulse wave velocity（baPWV）measurement is a convenient and noninvasive method to assess the human arterial stiffness.In clinical practice and research,baPWV is widely used for screening of early vascular lesion and assessment of cardiovascular risk.An acquisition system for brachial and ankle pulse waveform was developed.The influence of three widely used pulse timing mark（PTM）methods on the baPWV measurement was investigated in 59 healthy subjects.The results show that,there are significant differences among the baPWV results using three PTM methods（P0.001）.Moreover,the choice of PTM methods also affects the relationship of baPWV with age and blood pressure.

关 键 词：臂踝脉搏波传播速度 脉搏波时标 年龄 血压 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]