氮杂环丙烷与腈的[3+2]环加成反应生成咪唑啉的研究进展  

Advance in Synthesis of Imidazoline by [3+2]-Cycloaddition of N-tosyl Aziridines with nitriles

作　　者：魏文珑[1] 杨学绮[1] 李兴[1] 常宏宏[1] 

机构地区：[1]太原理工大学化学化工学院,山西太原030024

出　　处：《化工时刊》2011年第3期44-47,共4页Chemical Industry Times

摘　　要：咪唑啉是一种非常重要的药物中间体,其通过氮杂环丙烷与腈的[3+2]环加成反应是非常有效合成方法。综述了这种方法的研究进展,并且进行了评价与展望。Imidazolines are useful intermediates for the preparation of drugs and relevant compounds,which are synthetized by [3＋2]-Cycloaddition of various substituted N-tosyl aziridines with nitriles as a quite efficient method.The research progress of this method was reviewed、evaluated and prospected.

关 键 词：咪唑啉 氮杂环丙烷 [3+2]环加成反应 合成方法 综述 

分 类 号：O621.25[理学—有机化学]