冠状动脉介入术中对比剂应用对肾功能影响的研究  

Clinical Study of Renal Function in Patients Undergoing Coronary Intervention

作　　者：关彦军[1] 戴晓燕[1] 赵龙[1] 彭道有[2] 李恭[1] 

机构地区：[1]新疆维吾尔自治区人民医院心内科,新疆乌鲁木齐830001 [2]新疆维吾尔自治区人民医院肾病科,新疆乌鲁木齐830001

出　　处：《现代生物医学进展》2011年第4期721-725,共5页Progress in Modern Biomedicine

摘　　要：目的:观察冠状动脉介入术后患者肾功能变化情况、CIN发生率及其相关危险因素。方法:选择从2009年12月至2010年3月在新疆维吾尔自治区人民医院心内科接受冠状动脉介入术的患者131人,测定介入术前5天内任何一天和术后48小时的Scr,分析CIN危险因素。结果:131例患者中有8例发生CIN,发病率为6.1%,Logistic多因素回归分析均显示糖尿病、年龄大于70岁、LVEF小于45%是CIN发生的独立危险因素。结论:糖尿病、LVEF<45%、年龄>70岁是CIN的独立危险因素。Objective：To study the risk factors of contrast-induced nephropathy（CIN） in patients undergoing coronary artery intervention.Methods：131 patients undergoing PCI or coronary angiograph from december 2009 to March 2010 were enrolled in this study.Levels of serum creatinine were determined 5 days before and at 2 days after coronary artery intervention.Result：Among the 131 patients,8 patients（6.1%） developed CIN.Identified by Logistic regression,volume of contrast-media more than 300ml,diabetes mellitus and age more than 70 years were independent risk factors of CIN.Conclusions：volume of contrast-media more than 300ml,diabetes mellitus and age more than 70 years were independent risk factors of CIN.

关 键 词：冠状动脉介入术 对比剂肾病 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]