马来酸曲美布汀联合美常安治疗腹泻型肠易激综合征  

Treatment of irritable bowel syndrome with trimebute maleate combined with medilac-S

作　　者：袁淑芳[1] 张嘉斌 陈方方[3] 

机构地区：[1]新疆医科大学第五附属医院消化科,乌鲁木齐830011 [2]新疆阿克陶县医院,阿克陶845550 [3]新疆医科大学第五附属医院神经内科,乌鲁木齐830011

出　　处：《中国新药杂志》2011年第7期616-618,共3页Chinese Journal of New Drugs

摘　　要：目的:评价联合应用马来酸曲美布汀与美常安胶囊对腹泻型肠易激综合征的临床疗效。方法:60例腹泻型肠易激综合征患者随机分为两组,每组各30例。对照组给予马来酸曲美布汀200 mg,tid;治疗组同时加用美常安胶囊500 mg,tid。两组疗程均为4周。观察患者的症状、大便次数、大便性状。结果:治疗组有效率为90%,对照组有效率为73.33%(P<0.05),治疗组治疗后缓解腹泻、腹痛症状优于对照组(P<0.05)。结论:美常安联合马来酸曲美布汀胶囊治疗肠易激综合征有效。Objective： To evaluate the therapeutic effect of trimebute maleate combined with medilac-S in the treatment of irritable bowel syndrome（IBS）.Methods： Sixty patients with IBS were randomly divided into two groups（n=30 in each group）.They were treated with 200 mg of trimebute maleate and 500 mg of medilac-S,po,tid;or with medilac-S,po,tid,alone（control group） for four weeks.The symptoms of patients,times and physical findings of stool were observed.Results： The overall efficacy rate was 90% in combination group,which was obviously higher than that in control group（73.33%,P〈0.05）.The effect on abdominal pain and diarrhea were significantly better in combination group than in control group（P〈0.05）.Conclusion： Trimebute maleate in combination with medilac-S is effective in the treatment of IBS.

关 键 词：肠易激综合征 马来酸曲美布汀 美常安胶囊 

分 类 号：R975[医药卫生—药品]