血β-人绒毛膜促性腺激素联合B超测定子宫内膜厚度用于诊断早期异位妊娠的临床价值  

Serum β- HCG combined with endometrial thickness measured by B - ultrasound for the diagnosis of early ectopic pregnancy

作　　者：张喜红[1] 李晓丽[1] 

机构地区：[1]郑州人民医院妇产科,450003

出　　处：《中国实用医刊》2011年第8期29-30,33,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨血β-人绒毛膜促性腺激素（G—HCG）联合B超测定子宫内膜厚度用于诊断早期畀位妊娠的临床价值。方法2005年6月至2009年6月郑州人民医院对168例异位妊娠疑似患者采用血B—HCG联合B超测定子宫内膜厚度，并将随访结果、孕龄、血β—HCG、子宫内膜厚度进行比较分析。结果149例资料完整，其中89例（59．73％）确诊为异位妊娠，46例（30．87％）宫内孕，14例（9．40％）自然流产。异位妊娠及正常宫内孕初诊测定血B—HCG分别为（842±434）IU／L、（1824±329）IU／L；子宫内膜厚度（10．2±1．4）mm、（14．5±1．7）mm；孕龄（6．1±0．4）周、（6．2±0．6）周。两组孕龄比较差异无统计学意义（P〉0．05），血β—HCG水平、子宫内膜厚度比较差异有统计学意义（P〈0．05）。以血B～HCG≤1500IU／L、子宫内膜厚度≤10mm为早期诊断异位妊娠界值时，诊断早期异位妊娠的敏感性为87．64％，特异性为73．33％，假阳性率为26．67％，假阴性率14．17％，阳性预测值为82．98％，阴性预测值为80．00％。结论当血β—HCG≤1500IU／L、子宫内膜厚度≤10mm对诊断早期异位妊娠具有重要参考价值。Objective To investigate the serum β-HCG combined with endometrial thickness was measured for the diagnosis of early ectopic pregnancy. Methods From Feb. 2005 to Feb. 2009, 168 cases of suspected eetopic pregnancy patients with serum β- HCG combined with endometrial thickness measurement, and the follow- up results, gestational age, serum β-HCG, endometrial thickness were comparative analysed in our Hospital. Results The 149 cases including 89 cases with complete data （59.73%） confirmed pseudo- pregnancy, 46 cases （30.87%） intrauterine pregnancy, 14 cases （9.40%） spontaneous abortion. Ectopic pregnancy and normal intrauterine pregnancy diagnosed determination of blood β- HCG was （842 ± 434） IU/L, （ 1824 ± 329） IU/L; endometrial thickness of （10.2±1.4）mm, （14.5±1.7）mm; gestational age （6.1 ±0.4） weeks, （6.2±0.6）weeks. Gestational age groups showed no significant difference （ P 〉 0.05 ） , serum β- HCG level, endometrial thickness difference was significant （ P 〈0.05）. And blood β-HCG≤ 1500 IU/L, endometrial thickness ≤10 mm for the early diagnosis of ectopic pregnancy term value, the sensitivity of early diagnosis of eetopie pregnancy was 87.64% , specificity of 73.33% , false positive rate was 26.67% , the false negative rate was 14. 17%, positive predictive value of 82.98%, negative predictive value of 80.00%. Conclusions When the blood β- HCG ≤1500 IU / L, endometrial thickness ≤10 mm in the diagnosis of early ectopic pregnancy has important reference value.

关 键 词：早期异位妊娠 血Β-人绒毛膜促性腺激素 子宫内膜厚度 诊断 

分 类 号：R714.22[医药卫生—妇产科学]