胸腺移植治疗神经系统免疫性疾病的研究  

Thymic transplantation for treatment of immune diseases in nervous system.

作　　者：刘敦贵[1] 叶心国[2] 陈知水[1] 彭雪明[3] 阮旭中[3] 

机构地区：[1]同济医科大学附属同济医院器官移植研究所,武汉430030 [2]湖北医科大学附属第一医院 [3]同济医科大学附属同济医院

出　　处：《中华器官移植杂志》1999年第4期240-241,共2页Chinese Journal of Organ Transplantation

摘　　要：目的　报告３０ 例神经系统免疫性疾病患者接受胚胎胸腺移植治疗。方法　胸腺取自于水囊引产死胎， 制成组织匀浆植入腹直肌或股前肌群内。结果　移植后半年内， 患者临床症状明显改善， 免疫状态调节至正常， 总的疗效达８６ ．７ ％ 。结论　胸腺移植作为一种治疗神经系统免疫性疾病的新方法值得进一步探讨研究。Objective Thirty cases of immune diseases (including multiple sclerosis, polymyositis, myasthenia gravis,gullian barre syndrome) in nervous system underwent the treatment of fetal thymic transplantation.Methods The thymus was harvested from abortive fetus of 20 to 30 pregnant weeks in health women by legal water capsule inducing labour. The tissue homogenate was prepared and implanted into the abdominal muscles or thigh muscles within 1?h. Result Six months after transplantation, the clinical symptoms were significantly improved, and immune status was regulated. The overall effective rate was 86.7% .Conclusion Thymic transplantation as a new method for treating immune diseases in nervous system is required to be further studied.

关 键 词：胸腺移植 免疫性疾病 治疗 

分 类 号：R655.7[医药卫生—外科学]