巨细胞病毒宫内感染与不良产史关系的探讨  

Relationship between intrauterine infection of cytomegalovirus and abnormal pregnances

作　　者：刘艳秋[1] 余世瑢[1] 罗文[1] 栾树清[1] 李宇中[1] 

机构地区：[1]江西省妇幼保健院遗传室,南昌330006

出　　处：《江西医药》1999年第5期274-275,共2页Jiangxi Medical Journal

摘　　要：目的　探讨异常妊娠史与宫内巨细胞病毒感染的关系。方法　应用聚合酶链反应（ＰＣＲ） 技术，对羊水标本进行巨细胞病毒检测。结果　研究组１６２ 例，检出阳性４１ 例，阳性率为２５ ．３１ ％ （４１／１６２） ；正常对照组１０６ 例，检出阳性４ 例，阳性率为３ ．７７ ％ （４／１０６） ；两组之间有显著差异（ Ｐ＜ ０ ．０１） 。结论　异常妊娠史孕妇再次感染巨细胞病毒可能性较大，应孕前查明原因，早期诊断、早期治疗，以减少病儿的再次出生。Objective\ To study the relationship between abnormal pregnances and intrauterine.infection of human cytomegalovirus (HCMV)Methods\ Amniotic fluid were detected for HCMV DNA by polymerase chain reaction(PCR)in 162 cases (study group)and 106 cases (contral group).Results\ \ 41 patients were positive in the study group with positive rate 25.31%(41/162) and 4 cases positive in the control group with positive rate 3.77%(4/106);There were a significan difference between two groups (P<0.01).Conclusions\ It is possible that women with previous abnomal pregnance might infect HCMV again.It is advise that women with previous pregnance be diagnosed if they infect HCMV again and treated before repregnance to reduce bearing of teratism babies again.

关 键 词：巨细胞病毒感染 宫内感染 异常妊娠史 PCR 

分 类 号：R714.251[医药卫生—妇产科学] R711.32[医药卫生—临床医学]