复杂型睡眠呼吸暂停综合征12例分析  

Study of 12 complex sleep apnea syndrome patients

作　　者：王洪冰[1] 张坤[1] 雷玉晶[1] 孙铁英[1] 

机构地区：[1]卫生部北京医院呼吸内科,100730

出　　处：《国际呼吸杂志》2011年第7期519-521,共3页International Journal of Respiration

摘　　要：目的 分析复杂型睡眠呼吸暂停综合征（complex sleep apnea syndrome,CompSAS）患者临床特点.方法 收集我院12例CompSAS患者作回顾性分析,比较经鼻持续气道正压通气（continuous positive airway pressure,CPAP）治疗前后睡眠质量、呼吸紊乱、压力变化情况.结果 12例CompSAS患者均为男性,体质量超重.CPAP压力滴定前经PSG检查诊断为以阻塞性呼吸暂停（OSA）、低通气为主的SAS,部分合并有中枢性呼吸暂停（CSA）、混合型呼吸暂停（MSA）.在CPAP压力滴定时OSA、低通气、MSA得以消除,但CSA显著增多,与治疗前比较有显著差异,但治疗后AHI仍有显著降低（P＜0.001）.但患者睡眠质量有所改善,平均S1＋S2时间减少,REM时间增多,与治疗前有显著差异;缺氧总时间、最低氧饱和度均显著改善（P＜0.001）.临床上无法给出一个合适的治疗压力.患者自觉症状部分改善.结论 CompSAS无法确定合适的CPAP治疗压力,但CPAP呼吸机能部分改善患者睡眠质量和氧合.Objective A retrospective study of 12 complex sleep apnea syndrome （CompSAS）patients. Methods 12 CompSAS patients diagnosed in our hospital were collected and a comparison of sleep quality, respiratory events, saturation were made before and after Auto-CPAP titration. Results 12 CompSAS patients were all male and overweighed. All were diagnosed sleep apnea syndrome with dominantly OSA and hypopnea. OSA, hypopnea and mixed apnea were all eliminatied but CSA emerged significantily on Auto-CPAP titration night. Oxygen saturation developed significantly and sleep quality improved in spite of CSA existing. But suitable therapeutic pressure could not be achieved. Conclusions Although a suitable therapeutic pressure could not be achieved for CompSAS patients but Auto-CPAP improved sleep quality and oxygen saturation somehow.

关 键 词：复杂型睡眠呼吸暂停综合征 持续气道正压通气 

分 类 号：R766[医药卫生—耳鼻咽喉科]