降防保心胶囊的质量标准研究  

Study on Quality Standard for Jiangfang Baoxin Capsule

作　　者：张敏娟[1] 陆曙[1] 金卓 胡敏敏[1] 

机构地区：[1]南京中医药大学无锡附属医院,江苏无锡214001 [2]江苏省无锡药品检验所,江苏无锡214020

出　　处：《南京中医药大学学报》2011年第2期189-191,共3页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏省无锡市卫生系统中医药科研项目(ZXM0807)

摘　　要：目的建立降防保心胶囊的质量标准。方法采用TLC鉴别制剂中防己、当归、川芎;采用HPLC法测定降防保心胶囊中粉防己碱的含量。结果在TLC色谱中均能检出防己、当归、川芎,粉防己碱在0.009 772~0.195 44 mg/mL范围呈良好的线性关系,r=0.999 9,平均回收率为94.90%,RSD为1.36%。结论该方法操作简单,可靠,重现性好,专属性强,可用于降防保心胶囊的内在质量控制。OBJECTIVE To establish the quality standard for Jiangfang Baoxin Capsule.METHODS The thin-layer chromatography was used to identify Radix Stephaniae Tetrandrae,Radix Angelicae Sinensis;Rhizoma Chuanxiong,and the content of Tetrandrine was determined by HPLC.RESULTS The spots in the TLC were clear and distinguished well,the linear range of Tetrandrine was 0.009 772～0.195 44 mg/mL（r=0.999 9）.The average rate recovery was 94.90% with RSD of 1.36%.CONCLUSION This method is simple,reliable and of good reproducibility and accuracy,so it can be used for quality control of Jiangfang Baoxin Capsule.

关 键 词：降防保心胶囊 质量标准 防己 当归 川芎 粉防己碱 薄层色谱 高效液相色谱 

分 类 号：R286[医药卫生—中药学]