GM-1治疗液化石油气中毒的疗效分析  

Therapeutic Effect of GM-1 for Treatment of Acute Liquefied Petroleum Gas Poisoning

作　　者：周艳霞[1] 白润涛[1] 龙霞[1] 

机构地区：[1]广东省深圳市第二人民医院

出　　处：《中西医结合心脑血管病杂志》2011年第4期444-446,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：广东省深圳市科技局基金项目(No.201003029)

摘　　要：目的观察神经节苷脂(GM-1)对急性液化石油气中毒患者的疗效。方法对50例急性液化石油气中毒患者随机分成两组,对照组予常规药物治疗,观察组在常规治疗基础上加用GM-1治疗,治疗前及治疗1个月后进行临床疗效评定及记忆商数(DQ)测评,并随访3个月后再进行DQ测评。结果治疗1个月后观察组总有效率为84%,高于对照组的52%(P<0.05),在治疗1个月及随访3个月后,观察组的DQ值均高于对照组(P<0.05或P<0.01)。结论 GM-1可明显改善液化石油气中毒患者的预后,尤其是记忆功能的改善,而且远期治疗效果更优。Objective To evaluate the clinical efficacy of gangliaside M1（GM-1）for treatment of acute liquefied petroleum gas poisoning.Methods Fifty patients（pts） with acute liquefied petroleum gas poisoning were randomly divided into two groups：Control group treated with routine treatments and treatment group treated with GM-1.The DQ of the two groups was evaluated after 30 days and three months.Results The total clinical effective rate was 84% in treatment group after 30 days,which was was significantly higher than that in control group（52%,P〈0.05）.The DQ score in treatment group was significantly higher than that in control group after 30 days and three months（P〈0.05）.Conclusion GM-1 could elevate the outcome of the acute liquefied petroleum gas poisoning,especially the memory function.The late result was better.

关 键 词：液化石油气 急性中毒 神经节苷脂 记忆商数 

分 类 号：R595.1[医药卫生—内科学]