Excel在残数法计算药物动力学参数中的应用  

The Application of the Software Excel to Process the Parameters of Pharmacokinetics

作　　者：缪菊连[1] 

机构地区：[1]大理学院药学院,云南大理671000

出　　处：《大理学院学报（综合版）》2011年第2期13-15,共3页Journal of Dali University

摘　　要：目的:探求残数法计算药物动力学参数的简单方法。方法:采用Excel对数据进行线性回归,得出曲线方程,根据截距和斜率计算K及Ka。结果:利用Excel能正确、快速计算出K及Ka值。结论:将Excel应用残数法计算K及Ka值能减少工作量,提高准确率及工作效率。Objective：To search a convenient way for processing the parameters of pharmacokinetics.Methods：The software Excel was applied to analyze pharmacokinetics data to draw the curve,obtain curve equation,and calculate the parameters of K and Ka according to slope and intercept.Results：The software Excel was an efficient and exact way to process the parameters of K and Ka.Conclusion：Using software Excel to process the pharmacokinetics parameters could reduce workload;improve accuracy and efficiency of data analysis.

关 键 词：EXCEL 残数法 药物动力学 

分 类 号：R969.1[医药卫生—药理学]