Direct Electrochemistry Transfer and Electrocatalysis of Hemoglobin Immobilized in Porous Mn_2O_3  

作　　者：SHI Lin-pu GAO Qiu-ming 

机构地区：[1]School of Chemistry and Environment, Beihang University, Beijing 100191, P. R. China [2]Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, P. R. China

出　　处：《Chemical Research in Chinese Universities》2011年第2期291-294,共4页高等学校化学研究（英文版）

基　　金：Supported by the National Basic Research Program of China(No.2011CB935700);the National Natural Science Foundation of China(No.U0734002)

摘　　要：Novel porous Mn2O3 with good crystallinity was synthesized via hard-template method. Hb-Mn2O3 na-nocomposite was prepared and used for biosensor construction. The Hb-Mn2O3-Nafion modified electrode shows fast direct electron transfer and displays good electrocatalytic response to the reduction of H2O2. The response time is less than 5 s, the sensitivity is as high as 493 μA·L·mmol-1·cm-2 in a linear range of 1-100 μmol/L, and the detection limit is 0.16 μmol/L. This modified electrode also shows good stability and reproducibility. This indicates that the porous Mn2O3 provides a good matrix for enzyme immobilization and biosensor construction.Novel porous Mn2O3 with good crystallinity was synthesized via hard-template method. Hb-Mn2O3 na-nocomposite was prepared and used for biosensor construction. The Hb-Mn2O3-Nafion modified electrode shows fast direct electron transfer and displays good electrocatalytic response to the reduction of H2O2. The response time is less than 5 s, the sensitivity is as high as 493 μA·L·mmol-1·cm-2 in a linear range of 1-100 μmol/L, and the detection limit is 0.16 μmol/L. This modified electrode also shows good stability and reproducibility. This indicates that the porous Mn2O3 provides a good matrix for enzyme immobilization and biosensor construction.

关 键 词：Porous Mn203 BIOSENSOR Direct electrochemistry ELECTROCATALYSIS HEMOGLOBIN 

分 类 号：O657.1[理学—分析化学] TQ244.1[理学—化学]