494例Ⅰ类切口手术围术期预防性应用抗菌药物调查分析  

Perioperative Application of Prophylactic Antibiotics in 494 Patients Undergoing Type I Incision Operation

作　　者：张士勇[1] 叶云[1] 程军[1] 王刚斌[1] 

机构地区：[1]安徽省蚌埠市第三人民医院药事办,蚌埠233000

出　　处：《中国医院用药评价与分析》2011年第3期232-234,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解Ⅰ类切口手术患者预防性应用抗菌药物的情况,评价用药合理性,加强抗菌药物的使用管理。方法:回顾性调查2010年1—6月归档病历中Ⅰ类切口手术患者有关抗菌药物的预防性应用情况。结果:494例Ⅰ类切口手术患者中395例使用了抗菌药物,使用率为79.96%。在初次给药方面,术前0.5～2 h、2～24 h和>24 h用药者分别为12例9、1例45例;术后用药者247例。在持续给药中,术后预防用药时间<3 d者30例、3～7 d者253例、>7 d者112例。术后单一用药者占66.84%,二联用药者占31.64%,三联用药者占1.52%。结论:该院Ⅰ类切口手术患者预防性使用抗菌药物存在指征把握不严、抗菌药物品种档次高、选用药时机不当以及过度用药等问题,有待进一步规范化管理。OBJECTIVE：To investigate the status and rationality of prophylactic use of antibiotics in patients undergoing type I incision operation and strengthen the management on the use of antibiotics.METHODS：The medical records of patients undergoing type I incision operation which filed between Jan.and June in 2010 were sampled from our hospital for retrospective analysis of prophylactic use of antibiotics.RESULTS：Among all the 494 cases,395 cases（79.96%） had prophylactic use of antibiotics.In the initial administration,12 cases received antibiotics at 0.5-2 h,91 cases at 2-24 h and 45 cases at 24 h preoperatively,and 247 received antibiotics postoperatively.In the continue medication,30 cases received antibiotics for 3 days,253 for 3-7 days and 112 for 7 days.Postoperatively,the patients using single,two antibiotics and three in combination represented 66.84%,31.64% and 1.52%,respectively.CONCLUSION：The problems existing in the use of prophylactic antibiotics for patients undergoing type I incision operation in this hospital included non-strict handling of indications of antibiotic use,high grade of antibiotics selectedi,mproper medication timing and excessive drug use etc,thus standardized management on the use of antibiotics remains to be done.

关 键 词：Ⅰ类切口 抗菌药物 预防用药 调查分析 

分 类 号：R978.1[医药卫生—药品]